Gout comorbidities: results from the Korean National Health and Nutrition Examination Survey.

IF 2 4区 医学 Q3 RHEUMATOLOGY
Hyemin Jeong, Young-Soo Chang, Chan Hong Jeon
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Abstract

Objectives: Gout is associated with several comorbidities. This study aimed to evaluate the prevalence of comorbidities in the Korean adult population with gout and investigated the association of gout with these comorbidities.

Methods: Data from 15,935 (weighted n = 39,049,167) participants aged 19 years and older in the Korean National Health and Nutrition Examination Survey from 2019 to 2021 were used for analysis. Weighted prevalence and odds ratios (OR) of comorbidities in individuals with gout were compared to a non-gout population.

Results: The weighted prevalence of gout was 2.1% (weighted n = 808,778). Among individuals with gout, 66.5% had metabolic syndrome, 54.9% had hypertension, 41.2% had hypercholesterolemia, 19.1% had diabetes, 13.5% had chronic kidney disease (CKD), 4.1% had myocardial infarction or angina, 3.8% had stroke, and 2.8% had rheumatoid arthritis (RA). After adjusting for socioeconomic and lifestyle characteristics, gout was independently associated with the increased prevalence of metabolic syndrome (male OR = 2.0, 95% confidence interval (CI): 1.5-2.8; female OR = 3.7, 95% CI: 1.5-9.2), hypercholesterolemia (male OR = 1.9, 95% CI: 1.4-2.5; female OR = 3.1, 95% CI: 1.3-7.5), CKD (male OR = 4.5, 95% CI: 2.7-7.3; female OR = 11.5, 95% CI: 4.1-32.1), and RA (male OR = 2.8, 95% CI: 1.1-7.1; female OR = 3.1, 95% CI: 1.1-8.7) compared to the non-gout population.

Conclusions: Gout was associated with several comorbidities, including RA, in both males and females. These results suggest that the prevention and treatment of comorbidities at the individual level, carried out by clinicians, and knowledge of these comorbidities would help guide health policies for the Korean population.

痛风合并症:韩国国民健康与营养调查的结果。
目的:痛风与多种合并症有关。本研究旨在评估韩国成人痛风患者的合并症患病率,并调查痛风与这些合并症的关联:分析采用了2019年至2021年韩国全国健康与营养调查中15,935名(加权n=39,049,167)19岁及以上参与者的数据。将痛风患者合并症的加权患病率和几率比(OR)与非痛风人群进行了比较:痛风的加权患病率为 2.1%(加权 n = 808 778)。在痛风患者中,66.5%患有代谢综合征,54.9%患有高血压,41.2%患有高胆固醇血症,19.1%患有糖尿病,13.5%患有慢性肾病(CKD),4.1%患有心肌梗死或心绞痛,3.8%患有中风,2.8%患有类风湿性关节炎(RA)。在对社会经济和生活方式特征进行调整后,痛风与代谢综合征(男性 OR = 2.0,95% 置信区间 (CI):1.5-2.8;女性 OR = 3.7,95% CI:1.5-9.2)、高胆固醇血症(男性 OR = 1.9,95% CI:1.4-2.5;女性 OR = 3.1,95% CI:1.3-7.5)、CKD(男性 OR = 4.5,95% CI:2.7-7.3;女性 OR = 11.5,95% CI:4.1-32.1)和 RA(男性 OR = 2.8,95% CI:1.1-7.1;女性 OR = 3.1,95% CI:1.1-8.7):结论:无论男性还是女性,痛风都与包括RA在内的多种合并症有关。这些结果表明,由临床医生在个人层面对合并症进行预防和治疗,以及对这些合并症的了解将有助于指导韩国人口的健康政策。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Advances in Rheumatology
Advances in Rheumatology Medicine-Rheumatology
CiteScore
4.00
自引率
4.30%
发文量
41
审稿时长
53 weeks
期刊介绍: Formerly named Revista Brasileira de Reumatologia, the journal is celebrating its 60th year of publication. Advances in Rheumatology is an international, open access journal publishing pre-clinical, translational and clinical studies on all aspects of paediatric and adult rheumatic diseases, including degenerative, inflammatory and autoimmune conditions. The journal is the official publication of the Brazilian Society of Rheumatology and welcomes original research (including systematic reviews and meta-analyses), literature reviews, guidelines and letters arising from published material.
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