Improving treatment plan and mental health in children with abdominal infection for broad-spectrum bacterial infections.

IF 3.9 4区医学 Q1 PSYCHIATRY

World Journal of Psychiatry Pub Date : 2024-09-19 DOI:10.5498/wjp.v14.i9.1319

Gui-Bo Wang, Xue-Feng Zhang, Bing Liang, Jie Lei, Jun Xue

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引用次数: 0

Abstract

Background: Pediatric abdominal infection is a common but serious disease that requires timely and effective treatment. In surgical treatment, accurate diagnosis and rational application of antibiotics are the keys to improving treatment effects.

Aim: To investigate the effect of broad-spectrum bacterial detection on postoperative antibiotic therapy.

Methods: A total of 100 children with abdominal infection who received surgical treatment in our hospital from September 2020 to July 2021 were grouped. The observation group collected blood samples upon admission and sent them for broad-spectrum bacterial infection nucleic acid testing, and collected pus or exudate during the operation for bacterial culture and drug sensitivity testing; the control group only sent bacterial culture and drug sensitivity testing during the operation.

Results: White blood cell count, C-reactive protein, procalcitonin, 3 days after surgery, showed better postoperative index than the control group (P < 0.05). The hospital stay in the observation group was significantly shorter than that in the control group. The hospitalization cost in the observation group was significantly lower than that in the control group, and the difference between the two groups was statistically significant (P < 0.05).

Conclusion: Early detection of broad-spectrum bacterial infection nucleic acids in pediatric abdominal infections can help identify pathogens sooner and guide the appropriate use of antibiotics, improving treatment outcomes and reducing medical costs to some extent.

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改善腹腔感染儿童广谱细菌感染的治疗方案和心理健康。

背景：小儿腹腔感染是一种常见但严重的疾病，需要及时有效的治疗。目的：探讨广谱细菌检测对术后抗生素治疗的影响：将2020年9月-2021年7月在我院接受手术治疗的100例腹腔感染患儿进行分组。观察组在入院时采集血样送检广谱细菌感染核酸检测，并在手术过程中采集脓液或渗出液进行细菌培养和药敏检测；对照组仅在手术过程中进行细菌培养和药敏检测：结果：观察组术后3天白细胞计数、C反应蛋白、降钙素原均优于对照组（P<0.05）。观察组的住院时间明显短于对照组。观察组的住院费用明显低于对照组，两组差异有统计学意义（P < 0.05）：结论：早期检测小儿腹腔感染中的广谱细菌感染核酸有助于尽早发现病原体，指导合理使用抗生素，在一定程度上改善治疗效果，降低医疗费用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

World Journal of Psychiatry PSYCHIATRY-

自引率

6.50%

发文量

110

期刊介绍： The World Journal of Psychiatry (WJP) is a high-quality, peer reviewed, open-access journal. The primary task of WJP is to rapidly publish high-quality original articles, reviews, editorials, and case reports in the field of psychiatry. In order to promote productive academic communication, the peer review process for the WJP is transparent; to this end, all published manuscripts are accompanied by the anonymized reviewers’ comments as well as the authors’ responses. The primary aims of the WJP are to improve diagnostic, therapeutic and preventive modalities and the skills of clinicians and to guide clinical practice in psychiatry.