Differences in Depressive Symptom Profile by Age Group in Koreans With Major Depressive Disorder: Results From Nationwide General Population Surveys.

IF 1.8 4区 医学 Q3 PSYCHIATRY
Psychiatry Investigation Pub Date : 2024-09-01 Epub Date: 2024-09-11 DOI:10.30773/pi.2024.0074
Jimin Lee, Byung-Soo Kim, Seong-Jin Cho, Jun-Young Lee, Jee Eun Park, Su Jeong Seong, Sung Man Chang
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Abstract

Objective: This study investigated to what extent a range of depressive symptoms was differentially present depending on age group in Korean population.

Methods: Data was pooled from five nationally representative surveys in which 29,418 respondents aged at least 18 years were interviewed face-to-face using the Korean version of the Composite International Diagnostic Interview. A total of 691 (2.1%) respondents were found to have had at least 1 episode of major depressive disorder (MDD) within the last 12 months. Logistic regression analysis was conducted to identify the association between age groups (18-39 years, 40-59 years, and 60 years or older) and 26 depressive symptoms among the respondents with MDD.

Results: Associations were observed between somatic symptoms-including insomnia, awakening 2 h earlier-and cognitive symptoms such as feelings of guilt, thoughts of death, and suicidal ideation with the older age group. Whereas, atypical depressive symptoms such as increased appetite, weight gain, and hypersomnia were associated with the younger age group. When adjusted for sociodemographic factors, symptoms such as depressed mood, awakening 2 h earlier, and feeling guilty in the older age group, and hypersomnia, psychomotor retardation, and worse in the morning in the younger age group still remained statistically significant. Furthermore, fatigue and decreased libido were newly associated with the younger age group.

Conclusion: The findings of this study revealed distinct patterns of symptomatology in MDD based on age groups. These differences should be considered owing to their potential relevance to treatment response and prognosis in the clinical setting.

患有重度抑郁症的韩国人不同年龄段的抑郁症状特征差异:全国普通人群调查的结果。
目的:本研究调查了韩国人口中不同年龄段的抑郁症状的不同程度:本研究调查了韩国人口中一系列抑郁症状在多大程度上因年龄组而异:在五项具有全国代表性的调查中,共对 29,418 名年龄在 18 岁以上的受访者进行了面对面访谈,采用的是韩国版的国际综合诊断访谈法。结果发现,共有 691 名受访者(2.1%)在过去 12 个月内至少发作过一次重度抑郁障碍(MDD)。我们对患有重度抑郁症的受访者进行了逻辑回归分析,以确定年龄组(18-39 岁、40-59 岁和 60 岁或以上)与 26 种抑郁症状之间的关联:结果发现,躯体症状(包括失眠、提前 2 小时醒来)与认知症状(如内疚感、死亡念头和自杀意念)之间的关系与年龄较大的组别有关。而非典型抑郁症状(如食欲增加、体重增加和嗜睡)则与年轻组相关。在对社会人口因素进行调整后,老年组的情绪低落、提前 2 小时醒来和内疚感等症状,以及年轻组的嗜睡、精神运动迟缓和晨起时病情加重等症状仍具有显著的统计学意义。此外,疲劳和性欲减退与年轻组也有新的关联:结论:本研究结果表明,不同年龄组的 MDD 症状模式各不相同。结论:本研究结果显示,不同年龄组的 MDD 症状模式各不相同,这些差异可能与临床治疗反应和预后有关,因此应加以考虑。
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来源期刊
CiteScore
4.10
自引率
3.70%
发文量
105
审稿时长
6-12 weeks
期刊介绍: The Psychiatry Investigation is published on the 25th day of every month in English by the Korean Neuropsychiatric Association (KNPA). The Journal covers the whole range of psychiatry and neuroscience. Both basic and clinical contributions are encouraged from all disciplines and research areas relevant to the pathophysiology and management of neuropsychiatric disorders and symptoms, as well as researches related to cross cultural psychiatry and ethnic issues in psychiatry. The Journal publishes editorials, review articles, original articles, brief reports, viewpoints and correspondences. All research articles are peer reviewed. Contributions are accepted for publication on the condition that their substance has not been published or submitted for publication elsewhere. Authors submitting papers to the Journal (serially or otherwise) with a common theme or using data derived from the same sample (or a subset thereof) must send details of all relevant previous publications and simultaneous submissions. The Journal is not responsible for statements made by contributors. Material in the Journal does not necessarily reflect the views of the Editor or of the KNPA. Manuscripts accepted for publication are copy-edited to improve readability and to ensure conformity with house style.
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