Multifunctional bioactive glass nanoparticles: surface-interface decoration and biomedical applications.

IF 5.6 1区 医学 Q1 MATERIALS SCIENCE, BIOMATERIALS
Regenerative Biomaterials Pub Date : 2024-09-06 eCollection Date: 2024-01-01 DOI:10.1093/rb/rbae110
Mi Chen, Yidan Wang, Pingyun Yuan, Lan Wang, Xiaocheng Li, Bo Lei
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引用次数: 0

Abstract

Developing bioactive materials with multifunctional properties is crucial for enhancing their biomedical applications in regenerative medicine. Bioactive glass nanoparticle (BGN) is a new generation of biomaterials that demonstrate high biocompatibility and tissue-inducing capacity. However, the hard nanoparticle surface and single surface property limited their wide biomedical applications. In recent years, the surface functional strategy has been employed to decorate the BGN and improve its biomedical applications in bone tissue repair, bioimaging, tumor therapy and wound repair. This review summarizes the progress of surface-interface design strategy, customized multifunctional properties and biomedical applications in detail. We also discussed the current challenges and further development of multifunctional BGN to meet the requirements of various biomedical applications.

多功能生物活性玻璃纳米颗粒:表面-界面装饰和生物医学应用。
开发具有多功能特性的生物活性材料对于提高其在再生医学中的生物医学应用至关重要。生物活性玻璃纳米粒子(BGN)是新一代生物材料,具有很高的生物相容性和组织诱导能力。然而,纳米粒子表面坚硬、表面性质单一,限制了其在生物医学领域的广泛应用。近年来,人们采用表面功能策略来装饰 BGN,提高其在骨组织修复、生物成像、肿瘤治疗和伤口修复等方面的生物医学应用。本综述详细总结了表面-界面设计策略、定制的多功能特性和生物医学应用方面的进展。我们还讨论了多功能 BGN 目前面临的挑战和进一步发展,以满足各种生物医学应用的要求。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Regenerative Biomaterials
Regenerative Biomaterials Materials Science-Biomaterials
CiteScore
7.90
自引率
16.40%
发文量
92
审稿时长
10 weeks
期刊介绍: Regenerative Biomaterials is an international, interdisciplinary, peer-reviewed journal publishing the latest advances in biomaterials and regenerative medicine. The journal provides a forum for the publication of original research papers, reviews, clinical case reports, and commentaries on the topics relevant to the development of advanced regenerative biomaterials concerning novel regenerative technologies and therapeutic approaches for the regeneration and repair of damaged tissues and organs. The interactions of biomaterials with cells and tissue, especially with stem cells, will be of particular focus.
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