Alexa Schincariol, Graziella Orrù, Henry Otgaar, Giuseppe Sartori, Cristina Scarpazza
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引用次数: 0
Abstract
Posttraumatic stress disorder (PTSD) is one of the most serious and incapacitating mental diseases that can result from trauma exposure. The exact prevalence of this disorder is not known as the literature provides very different results, ranging from 2.5% to 74%. The aim of this umbrella review is to provide an estimation of PTSD prevalence and to clarify whether the prevalence depends on the assessment methods applied (structured interview v. self-report questionnaire) and on the nature of the traumatic event (interpersonal v. not-interpersonal). A systematic search of major databases and additional sources (Google Scholar, EBSCO, Web of Science, PubMed, Galileo Discovery) was conducted. Fifty-nine reviews met the criteria of this umbrella review. Overall PTSD prevalence was 23.95% (95% confidence interval 95% CI 20.74-27.15), with no publication bias or significant small-study effects, but a high level of heterogeneity between meta-analyses. Sensitivities analyses revealed that these results do not change after removing meta-analysis also including data from underage participants (23.03%, 95% CI 18.58-27.48), nor after excluding meta-analysis of low quality (24.26%, 95% CI 20.46-28.06). Regarding the impact of diagnostic instruments on PTSD prevalence, the results revealed a lack of significant differences in PTSD prevalence when structured v. self-report instruments were applied (p = 0.0835). Finally, PTSD prevalence did not differ following event of intentional (25.42%, 95% CI 19.76-31.09) or not intentional (22.48%, 95% CI 17.22-27.73) nature (p = 0.4598). The present umbrella review establishes a robust foundation for future research and provides valuable insights on PTSD prevalence.
创伤后应激障碍(PTSD)是因遭受创伤而导致的最严重、最令人丧失能力的精神疾病之一。这种疾病的确切患病率尚不清楚,因为文献提供的结果大相径庭,从 2.5% 到 74% 不等。本综述旨在估算创伤后应激障碍的患病率,并澄清患病率是否取决于所采用的评估方法(结构化访谈与自我报告问卷)以及创伤事件的性质(人际与非人际)。我们对主要数据库和其他来源(Google Scholar、EBSCO、Web of Science、PubMed、Galileo Discovery)进行了系统检索。59 篇综述符合本综述的标准。创伤后应激障碍的总体患病率为 23.95%(95% 置信区间 95% CI 20.74-27.15),没有发表偏差或显著的小型研究效应,但荟萃分析之间存在高度异质性。敏感性分析表明,在剔除包含未成年参与者数据的荟萃分析(23.03%,95% CI 18.58-27.48)或剔除低质量的荟萃分析(24.26%,95% CI 20.46-28.06)后,上述结果没有变化。关于诊断工具对创伤后应激障碍患病率的影响,研究结果显示,在使用结构化工具和自我报告工具时,创伤后应激障碍患病率没有显著差异(p = 0.0835)。最后,创伤后应激障碍发病率在事件性质为蓄意(25.42%,95% CI 19.76-31.09)或非蓄意(22.48%,95% CI 17.22-27.73)时没有差异(p = 0.4598)。本综述为今后的研究奠定了坚实的基础,并为创伤后应激障碍的患病率提供了宝贵的见解。
期刊介绍:
Now in its fifth decade of publication, Psychological Medicine is a leading international journal in the fields of psychiatry, related aspects of psychology and basic sciences. From 2014, there are 16 issues a year, each featuring original articles reporting key research being undertaken worldwide, together with shorter editorials by distinguished scholars and an important book review section. The journal''s success is clearly demonstrated by a consistently high impact factor.