Periorbital Tuberculosis: A Rare Case of Extrapulmonary Tuberculosis.

IF 2.6 4区医学 Q2 OPHTHALMOLOGY

Ocular Immunology and Inflammation Pub Date : 2025-02-01 Epub Date: 2024-09-25 DOI:10.1080/09273948.2024.2407460

Aylin Var, Yusuf Uysal, Mehmet Kuruş, Yağmur Seda Yeşiltaş, Uğur Bozlar, Şeref Özkara, Ali Albay

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引用次数: 0

Abstract

Purpose: Orbital/periorbital tuberculosis (TB) is an uncommon manifestation of extrapulmonary TB, presenting diagnostic challenges due to its varied clinical features that can mimic other diseases. This report aims to present a rare case of periorbital TB in a young man.

Methods: Case report.

Results: A 36-year-old man presented with painless left periorbital swelling and discharge following facial trauma. Despite initial treatment with antibiotics elsewhere, symptoms persisted. Imaging revealed a periorbital abscess with adjacent bone involvement. Microbiologic studies demonstrated Mycobacterium tuberculosis complex growth, confirming TB. There was no evidence of systemic TB. The patient received anti-tuberculosis therapy. At the 8-month follow-up, he remained symptom-free.

Conclusion: Orbital/periorbital TB, although rare, should be taken into consideration in regions with high TB prevalence when dealing with chronic, non-resolving periorbital lesions. Advanced imaging and molecular diagnostics play crucial roles in confirming the diagnosis, especially given the low sensitivity of traditional culture methods for extrapulmonary TB.

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眶周结核病：肺外结核的罕见病例。

目的：眼眶/眶周结核病（TB）是肺外结核病的一种不常见表现，由于其临床特征多样，可与其他疾病混淆，因此给诊断带来了挑战。本报告旨在介绍一例罕见的年轻男性眶周结核病例：方法：病例报告：一名 36 岁的男子在面部外伤后出现左侧眶周无痛性肿胀和分泌物。尽管最初在其他地方使用了抗生素治疗，但症状依然存在。影像学检查发现眶周脓肿并累及邻近骨骼。微生物学检查显示有结核分枝杆菌复合体生长，证实为肺结核。没有全身结核病的证据。患者接受了抗结核治疗。随访8个月，患者仍无症状：眼眶/眶周结核病虽然罕见，但在结核病高发地区，在处理慢性、无缓解的眶周病变时应加以考虑。先进的成像和分子诊断技术在确诊中起着至关重要的作用，尤其是考虑到传统培养方法对肺外结核病的敏感性较低。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Ocular Immunology and Inflammation 医学-眼科学

CiteScore

6.20

自引率

15.20%

发文量

285

审稿时长

6-12 weeks

期刊介绍： Ocular Immunology & Inflammation ranks 18 out of 59 in the Ophthalmology Category.Ocular Immunology and Inflammation is a peer-reviewed, scientific publication that welcomes the submission of original, previously unpublished manuscripts directed to ophthalmologists and vision scientists. Published bimonthly, the journal provides an international medium for basic and clinical research reports on the ocular inflammatory response and its control by the immune system. The journal publishes original research papers, case reports, reviews, letters to the editor, meeting abstracts, and invited editorials.