Mirids secrete a TOPLESS targeting protein to enhance JA-mediated defense and gossypol accumulation for antagonizing cotton bollworms on cotton plants.

IF 17.1 1区生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Molecular Plant Pub Date : 2024-11-04 Epub Date: 2024-09-24 DOI:10.1016/j.molp.2024.09.008

Yu-Pei Mu, Dian-Yang Chen, Yu-Jie Liu, Ming-Yu Zhu, Xian Zhang, Yin Tang, Jia-Ling Lin, Mu-Yang Wang, Xiao-Xia Shangguan, Xiao-Ya Chen, Chengshu Wang, Ying-Bo Mao

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引用次数: 0

Abstract

Most coexisting insect species exhibit stunted growth compared to individual species on plants. This phenomenon reflects an interspecific antagonism drawing extensive attention, while the underlying mechanisms remain largely uncharacterized. Mirids (Apolygus lucorum) and cotton bollworms (Helicoverpa armigera) are two common cotton pests. We identified a secretory protein, ASP1, from the oral secretion of mirids, found in the nucleus of mirid-infested cotton leaves. ASP1 specifically targets the transcriptional co-repressor TOPLESS (TPL) and inhibits NINJA-mediated recruitment of TPL, promoting plant defense response and gossypol accumulation in cotton glands. ASP1-enhanced defense inhibits the growth of cotton bollworms on cotton plants, while having limited impact on mirids. The mesophyll-feeding characteristic allows mirids to avoid most cotton glands, invalidating cotton defense. Our investigation reveals the molecular mechanism by which mirids employ cotton defense to selectively inhibit the feeding of cotton bollworms.

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Mirids分泌一种TOPLESS靶向蛋白，以增强JA介导的防御和棉酚积累，从而对抗棉花植株上的棉铃虫。

与植物上的单一物种相比，大多数共存的昆虫物种都表现出生长迟缓。这种现象反映了一种种间拮抗作用，引起了广泛关注，但其潜在的机制在很大程度上仍不为人所知。棉铃虫（Helicoverpa armigera）和棉蚜（Apolygus lucorum）是棉田中常见的两种害虫。我们从棉铃虫的口腔分泌物中发现了一种分泌蛋白 ASP1，这种蛋白存在于被棉铃虫侵染的棉花叶片的细胞核中。ASP1特异性地靶向转录核心抑制因子TOPLESS（TPL），抑制NINJA介导的TPL招募，从而促进植物防御反应和棉酚在棉花腺体中的积累。ASP1 增强的防御能力可抑制棉铃虫在棉花植株上的生长，但对蚜虫的影响很小。中叶取食的特性使蚜虫能够避开大多数棉花腺体，从而使棉花防御失效。我们的研究揭示了蜃虫利用棉花防御选择性抑制棉铃虫取食的分子机制。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Molecular Plant 植物科学-生化与分子生物学

CiteScore

37.60

自引率

2.20%

发文量

1784

审稿时长

1 months

期刊介绍： Molecular Plant is dedicated to serving the plant science community by publishing novel and exciting findings with high significance in plant biology. The journal focuses broadly on cellular biology, physiology, biochemistry, molecular biology, genetics, development, plant-microbe interaction, genomics, bioinformatics, and molecular evolution. Molecular Plant publishes original research articles, reviews, Correspondence, and Spotlights on the most important developments in plant biology.