Global Trends in Melanoma Burden: A Comprehensive Analysis from the Global Burden of Disease Study, 1990-2021.

IF 12.8 1区医学 Q1 DERMATOLOGY

Journal of the American Academy of Dermatology Pub Date : 2024-09-27 DOI:10.1016/j.jaad.2024.09.035

Yulin Sun, Yiming Shen, Qian Liu, Hao Zhang, Lingling Jia, Yi Chai, Hua Jiang, Minjuan Wu, Yufei Li

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引用次数: 0

Abstract

Background: Melanoma, a significant global health concern, has shown evolving epidemiological trends. Accurate estimation of melanoma's burden is essential for public health strategies and interventions.

Objectives: This study aims to estimate the incidence, mortality, and disability-adjusted life years (DALYs) for melanoma, stratified by region, gender, and age group, from 1990 to 2021.

Methods: Using data from the Global Burden of Disease (GBD) 2021, we analyzed melanoma incidence, mortality rates, and DALYs in 204 countries from 1990 to 2021. These metrics were age-standardized and stratified by age, sex, Socio-Demographic Index (SDI), region, and country. The estimated annual percentage change (EAPC) was calculated to track temporal trends.

Results: Our study shows a substantial global increase in melanoma incidence, with significant disparities between genders and age groups. Higher SDI regions had increased incidence rates, while global mortality declined, likely due to improved detection and treatment.

Limitations: The reliance on estimates and models may introduce bias due to variability in disease definitions, diagnostic criteria, and data collection methods.

Conclusion: This study underscores the dynamic nature of melanoma's burden and the need for targeted, age-specific, and gender-specific interventions. Continued research is essential to address the growing challenges posed by melanoma.

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全球黑色素瘤负担趋势：1990-2021 年全球疾病负担研究综合分析》。

背景：黑色素瘤是全球关注的重大健康问题，其流行病学趋势不断变化。准确估计黑色素瘤的负担对公共卫生战略和干预措施至关重要：本研究旨在按地区、性别和年龄组对 1990 年至 2021 年期间黑色素瘤的发病率、死亡率和残疾调整生命年（DALYs）进行估算：利用《2021 年全球疾病负担》（GBD）的数据，我们分析了 1990 年至 2021 年期间 204 个国家的黑色素瘤发病率、死亡率和残疾调整生命年。这些指标已按年龄标准化，并按年龄、性别、社会人口指数（SDI）、地区和国家进行了分层。通过计算估计年度百分比变化（EAPC）来跟踪时间趋势：我们的研究表明，全球黑色素瘤发病率大幅上升，不同性别和年龄组之间存在显著差异。SDI 较高的地区发病率上升，而全球死亡率下降，这可能是由于检测和治疗的改善：局限性：由于疾病定义、诊断标准和数据收集方法的差异，对估计值和模型的依赖可能会带来偏差：这项研究强调了黑色素瘤负担的动态性质，以及采取有针对性、针对特定年龄和性别的干预措施的必要性。要应对黑色素瘤带来的日益严峻的挑战，继续开展研究至关重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of the American Academy of Dermatology 医学-皮肤病学

CiteScore

8.60

自引率

5.80%

发文量

2023

审稿时长

49 days

期刊介绍： The Journal of the American Academy of Dermatology (JAAD) is the official scientific publication of the American Academy of Dermatology (AAD). Its primary goal is to cater to the educational requirements of the dermatology community. Being the top journal in the field, JAAD publishes original articles that have undergone peer review. These articles primarily focus on clinical, investigative, and population-based studies related to dermatology. Another key area of emphasis is research on healthcare delivery and quality of care. JAAD also highlights high-quality, cost-effective, and innovative treatments within the field. In addition to this, the journal covers new diagnostic techniques and various other topics relevant to the prevention, diagnosis, and treatment of skin, hair, and nail disorders.