Occlusive retinal vasculitis associated with intravitreal Faricimab injections.

IF 2.9 Q1 OPHTHALMOLOGY
Felix F Reichel, Peter Kiraly, Roopa Vemala, Stella Hornby, Samantha R De Silva, M Dominik Fischer
{"title":"Occlusive retinal vasculitis associated with intravitreal Faricimab injections.","authors":"Felix F Reichel, Peter Kiraly, Roopa Vemala, Stella Hornby, Samantha R De Silva, M Dominik Fischer","doi":"10.1186/s12348-024-00429-7","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>We describe a case of occlusive vasculitis associated with intravitreal Faricimab (Vabysmo) injections.</p><p><strong>Methods: </strong>A retrospective case report.</p><p><strong>Results: </strong>A 52-year old man treated with monthly Faricimab injections for diabetic macula oedema presented with sudden reduced vision, new retinal hemorrhages, significant retinal vascular occlusions and ischemia. After screening for differential diagnoses was unremarkable, the patient was treated with oral and intravitreal steroid therapy under which the occlusive vasculitis was stabilized.</p><p><strong>Conclusion: </strong>Occlusive vasculitis, though rare, is a potential complication of Faricimab therapy. Comprehensive reporting and large-scale analyses are essential to better understand and manage this adverse event.</p>","PeriodicalId":16600,"journal":{"name":"Journal of Ophthalmic Inflammation and Infection","volume":null,"pages":null},"PeriodicalIF":2.9000,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11436497/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Ophthalmic Inflammation and Infection","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1186/s12348-024-00429-7","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Purpose: We describe a case of occlusive vasculitis associated with intravitreal Faricimab (Vabysmo) injections.

Methods: A retrospective case report.

Results: A 52-year old man treated with monthly Faricimab injections for diabetic macula oedema presented with sudden reduced vision, new retinal hemorrhages, significant retinal vascular occlusions and ischemia. After screening for differential diagnoses was unremarkable, the patient was treated with oral and intravitreal steroid therapy under which the occlusive vasculitis was stabilized.

Conclusion: Occlusive vasculitis, though rare, is a potential complication of Faricimab therapy. Comprehensive reporting and large-scale analyses are essential to better understand and manage this adverse event.

与玻璃体内注射 Faricimab 相关的闭塞性视网膜血管炎。
目的:我们描述了一例与玻璃体内注射法利西单抗(Vabysmo)相关的闭塞性血管炎病例:方法:回顾性病例报告:一名52岁的男性患者因糖尿病黄斑水肿每月注射一次法利单抗,突然出现视力下降、新的视网膜出血、视网膜血管明显闭塞和缺血。经过鉴别诊断筛查无异常后,患者接受了口服和玻璃体内类固醇治疗,闭塞性脉管炎得到了稳定:结论:闭塞性血管炎虽然罕见,但却是法利单抗治疗的潜在并发症。综合报告和大规模分析对于更好地了解和管理这一不良事件至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
CiteScore
3.80
自引率
3.40%
发文量
39
审稿时长
13 weeks
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信