Unveiling the mosaic: comparing demographics and outcomes in traumatic vs. non-traumatic spinal cord injuries.

IF 3.3 3区 医学 Q1 REHABILITATION
Emanuela Lena, Laura Timelli, Sergio DI Fonzo, Angelo Tonini, Valerio Pisani, Caterina Garcovich, Emanuela Covella, Federica Tamburella, Giorgio Scivoletto
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引用次数: 0

Abstract

Background: This study analyzed the percentage of patients with nontraumatic spinal cord injury (SCI) which is increasing with the increase of population age. However, little is known about the effect of the etiology of SCI on the outcome of these subjects.

Aim: The aim of this study was to investigate functional and neurological outcomes in patients with traumatic and nontraumatic spinal cord lesions, with a focus on factors influencing rehabilitation outcomes.

Design: The design of this study was that of a retrospective analysis of prospectively recorded data.

Setting: The setting of this analysis was a single Spinal Unit in Italy.

Population: The population included 1080 subjects, of which 599 (55%) had injuries of traumatic origin and 481 (45%) had nontraumatic injuries.

Methods: International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI), the Spinal Cord Independence Measure (SCIM) and the Walking Index for Spinal Cord Injury (WISCI) were utilized as measurement tools. Multivariate (backwards selection, P=0.20) logistic regression was used to assess the associations of "complication during hospitalization," "bowel management autonomy," "spontaneous micturition," "home destination" and "neurological improvement" with the following variables: etiology, age, sex, lesion level and severity and length of stay. Multivariate (backwards selection, P=0.20) negative binomial regression was used to assess the relative risks of higher SCIM and WISCI Scores at discharge after adjusting for the abovementioned variables.

Results: Our work highlighted several significant differences between the traumatic and nontraumatic groups (including age, sex, lesion severity, and time from lesion onset to admission). Both groups exhibited comparable improvements in neurological and functional status, although some data were in favor of subjects with traumatic lesions. However, the regression analyses demonstrated that the main factors impacting the neurological and functional status at discharge were age, lesion level and severity, rather than the etiology of the lesion.

Conclusions: Our study provides valuable insights into the rehabilitation trajectories of traumatic and nontraumatic spinal cord injuries and demonstrates that the cause of SCI has no impact on rehabilitation outcomes.

Clinical rehabilitation impact: An understanding of neurological and functional recovery after spinal cord lesions is essential for answering patients' questions about their potential functional capabilities. It also assists in determining the necessary resources for inpatient rehabilitation and post discharge care. Moreover, the possession of a thorough grasp of the course and factors influencing the natural recovery of a spinal cord lesion is now a scientific necessity and is crucial for assessing the efficacy of new pharmacological and rehabilitative methods.

揭开马赛克的面纱:比较外伤性与非外伤性脊髓损伤的人口统计学特征和结果。
研究背景这项研究分析了非创伤性脊髓损伤(SCI)患者的比例,随着人口年龄的增长,这一比例也在不断增加。目的:本研究旨在调查外伤性和非外伤性脊髓损伤患者的功能和神经功能预后,重点关注影响康复预后的因素:本研究的设计是对前瞻性记录数据进行回顾性分析:环境:分析的环境是意大利的一个脊柱科:研究对象:1080名受试者,其中599人(55%)为创伤性损伤,481人(45%)为非创伤性损伤:采用脊髓损伤神经学分类国际标准(ISNCSCI)、脊髓独立性测量(SCIM)和脊髓损伤行走指数(WISCI)作为测量工具。多变量(逆向选择,P=0.20)逻辑回归用于评估 "住院期间并发症"、"自主排便"、"自主排尿"、"回家目的地 "和 "神经功能改善 "与下列变量的相关性:病因、年龄、性别、病变程度和严重性以及住院时间。在对上述变量进行调整后,采用多变量(反向选择,P=0.20)负二项回归评估出院时 SCIM 和 WISCI 评分较高的相对风险:我们的研究突显了创伤组和非创伤组之间的一些显著差异(包括年龄、性别、病变严重程度以及从病变发生到入院的时间)。两组患者在神经和功能状态方面的改善程度相当,但有些数据对创伤性病变的受试者更有利。然而,回归分析表明,影响出院时神经和功能状况的主要因素是年龄、病变程度和严重性,而不是病因:我们的研究为创伤性和非创伤性脊髓损伤的康复轨迹提供了宝贵的见解,并证明了脊髓损伤的病因对康复结果没有影响:临床康复的影响:了解脊髓损伤后的神经和功能恢复情况对于回答患者有关其潜在功能能力的问题至关重要。它还有助于确定住院康复和出院后护理所需的资源。此外,全面掌握脊髓病变后自然恢复的过程和影响因素现在已成为科学的必要条件,对于评估新的药物和康复方法的疗效至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
8.50
自引率
4.40%
发文量
162
审稿时长
6-12 weeks
期刊介绍: The European Journal of Physical and Rehabilitation Medicine publishes papers of clinical interest in physical and rehabilitation medicine.
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