{"title":"Full thickness macular hole after intravitreal brolucizumab injection in neovascular age-related macular degeneration.","authors":"Sang Hyeok Lee, Mee Yon Lee","doi":"10.1177/11206721241286708","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>To describe a case of full thickness macular hole after intravitreal brolucizumab injection in neovascular age-related macular degeneration, which has not been reported to date.</p><p><strong>Case description: </strong>A 65-year-old male patient received brolucizumab intravitreal injection therapy for neovascular macular degeneration of the right eye. He received multiple intravitreal anti-VEGF injections on a pro re nata regimen and developed a full thickness macular hole.</p><p><strong>Outcome: </strong>Surgical treatment was performed with pars plana vitrectomy of the right eye. Full thickness macular hole was successfully treated.</p><p><strong>Conclusion: </strong>Although a full thickness macular hole following intravitreal brolucizumab injection is an uncommon complication, it requires caution.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":1.4000,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"European Journal of Ophthalmology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1177/11206721241286708","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Purpose: To describe a case of full thickness macular hole after intravitreal brolucizumab injection in neovascular age-related macular degeneration, which has not been reported to date.
Case description: A 65-year-old male patient received brolucizumab intravitreal injection therapy for neovascular macular degeneration of the right eye. He received multiple intravitreal anti-VEGF injections on a pro re nata regimen and developed a full thickness macular hole.
Outcome: Surgical treatment was performed with pars plana vitrectomy of the right eye. Full thickness macular hole was successfully treated.
Conclusion: Although a full thickness macular hole following intravitreal brolucizumab injection is an uncommon complication, it requires caution.
期刊介绍:
The European Journal of Ophthalmology was founded in 1991 and is issued in print bi-monthly. It publishes only peer-reviewed original research reporting clinical observations and laboratory investigations with clinical relevance focusing on new diagnostic and surgical techniques, instrument and therapy updates, results of clinical trials and research findings.