Management Strategies for Patients with Non-Infectious Cystitis: A Review of the Literature.

IF 2.5 2区医学 Q2 UROLOGY & NEPHROLOGY

Current Urology Reports Pub Date : 2024-09-30 DOI:10.1007/s11934-024-01236-2

Jawad Aqeel, Kathryn Sawyer, Yu Zheng, Priyanka Gupta

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Abstract

Purpose of review: The management of noninfectious cystitis continues to evolve as new treatments continue to be developed and investigated. This review aims to synthesize the most recent data regarding management strategies for noninfectious cystitis focused on non-ulcerative, ulcerative, eosinophilic, and ketamine-induced cystitis.

Recent findings: Several novel treatments have shown promise as management options including combination antihistamine therapy, phosphodiesterase 5 inhibitors, alpha lipoic acid supplements, and onabotulinumtoxin A. Recent studies have also found pentosan polysulfate sodium to have adverse ophthalmologic effects. For patients with ulcerative cystitis, recent research has shown that fulguration with or without triamcinolone injections should not be delayed. The treatment of noninfectious cystitis should be patient specific based on factors including etiology and symptom profile. Multimodal regimens are often the most effective. Treatment should be started with conservative options and escalated as necessary to oral treatments, intravesical options, or procedural management.

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非感染性膀胱炎患者的管理策略：文献综述。

回顾的目的：随着新疗法的不断开发和研究，非感染性膀胱炎的治疗方法也在不断发展。本综述旨在综合有关非感染性膀胱炎治疗策略的最新数据，重点关注非溃疡性膀胱炎、溃疡性膀胱炎、嗜酸性膀胱炎和氯胺酮诱发的膀胱炎：最近的研究发现，硫酸戊聚糖钠对眼科有不良影响。对于溃疡性膀胱炎患者，最近的研究表明，无论是否注射三苯氧胺，都不应延迟膀胱充盈术。非感染性膀胱炎的治疗应根据病因和症状等因素因人而异。多模式疗法通常最为有效。治疗应从保守疗法开始，必要时升级为口服药物、膀胱内注射疗法或手术治疗。

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来源期刊

Current Urology Reports UROLOGY & NEPHROLOGY-

CiteScore

4.60

自引率

3.80%

发文量

期刊介绍： This journal intends to review the most important, recently published findings in the field of urology. By providing clear, insightful, balanced contributions by international experts, the journal elucidates current and emerging approaches to the care and prevention of urologic diseases and conditions. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas, such as benign prostatic hyperplasia, erectile dysfunction, female urology, and kidney disease. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research. Commentaries from well-known figures in the field are also provided.