Severe Optic Neuropathy Induced by Very Prolonged Tedizolid as Suppressive Therapy: Description of a Case Report and Implication for Better Assessment.

IF 3.8 4区医学 Q2 IMMUNOLOGY

Open Forum Infectious Diseases Pub Date : 2024-09-24 eCollection Date: 2024-09-01 DOI:10.1093/ofid/ofae517

F Coustilleres, E M Thillard, R K Khanna, S Olivereau, M Ouaissi, N Pansu, M L Le Lez

引用次数: 0

Abstract

The long-term tolerability of linezolid is low because of mitochondrial toxicity, whereas tedizolid may represent a better option for suppressive therapy. We report a first presumed case of tedizolid-associated optic neuropathy after a very prolonged (18-month) intake and believe that screening for optic neuropathy should be considered for patients undergoing tedizolid suppression.

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长时间泰迪唑胺抑制疗法诱发的严重视神经病变：病例报告描述及更好评估的意义。

由于线粒体毒性，利奈唑胺的长期耐受性较低，而泰迪唑胺可能是抑制性治疗的更好选择。我们报告了第一例推测与泰迪唑胺相关的视神经病变病例，患者服用泰迪唑胺的时间非常长（18 个月），因此我们认为应考虑对接受泰迪唑胺抑制治疗的患者进行视神经病变筛查。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Open Forum Infectious Diseases Medicine-Neurology (clinical)

CiteScore

6.70

自引率

4.80%

发文量

630

审稿时长

9 weeks

期刊介绍： Open Forum Infectious Diseases provides a global forum for the publication of clinical, translational, and basic research findings in a fully open access, online journal environment. The journal reflects the broad diversity of the field of infectious diseases, and focuses on the intersection of biomedical science and clinical practice, with a particular emphasis on knowledge that holds the potential to improve patient care in populations around the world. Fully peer-reviewed, OFID supports the international community of infectious diseases experts by providing a venue for articles that further the understanding of all aspects of infectious diseases.