Efficacy of Thai Herbal Extract Oral Care Products in Promoting Antimicrobial Health Among Healthy Volunteers.

IF 0.7 Q4 PHARMACOLOGY & PHARMACY

Journal of pharmacy & bioallied sciences Pub Date : 2024-07-01 Epub Date: 2024-07-31 DOI:10.4103/jpbs.jpbs_422_24

Pimporn Thongmuang, Kanittada Thongkao, Robert Wyn Owen, Yuttana Sudjaroen

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引用次数: 0

Abstract

Background: Reducing the levels of oral microbials, including Streptococcus mutans, Candida albicans, and Lactobacilli sp., would provide the prevention of dental caries and oral illness.

Aims: To assess the antimicrobial effectiveness against oral pathogens of oral care products that contain urginea maritima extract (UM) extract, including lozenges, mouth spray, and mouthwash.

Methods: The skin irritation test was conducted on each product compared with controls in healthy participants (n = 10) by the 24-hour closed obstruction patch test. The elimination of oral pathogens in participants (n = 30) before and after product usage (as per the instruction) was assessed using a modified dip slide test.

Result: The physical appearance and stability of oral care products were almost preferable. When added to oral care products for oral health maintenance, the cariogenic bacteria S. mutans, Candida species, and Lactobacilli species have been found to exhibit antimicrobial activity.

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泰国草药提取物口腔护理产品在促进健康志愿者抗菌健康方面的功效。

背景：降低口腔微生物（包括变异链球菌、白色念珠菌和乳酸杆菌）的水平，有助于预防龋齿和口腔疾病。目的：评估含海胆提取物（UM）的口腔护理产品（包括含片、口腔喷雾剂和漱口水）对口腔病原体的抗菌效果：方法：通过 24 小时封闭阻塞贴片试验，对每种产品进行皮肤刺激试验，并与健康参与者（10 人）的对照组进行比较。使用改良的浸渍载玻片试验，评估参与者（n = 30）在使用产品前后（按照说明）口腔病原体的消除情况：结果：口腔护理产品的物理外观和稳定性基本符合要求。当添加到口腔护理产品中用于口腔健康维护时，已发现致龋菌 S.mutans、念珠菌和乳酸杆菌具有抗菌活性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of pharmacy & bioallied sciences

CiteScore

1.40

自引率

0.00%

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