Neuro-musculoskeletal side effects related to COVID-19 vaccines; A cross sectional study in Iranian healthcare workers

IF 2.3 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Clinical Epidemiology and Global Health Pub Date : 2024-09-19 DOI:10.1016/j.cegh.2024.101691

Masoumeh ZoghAli , Fateme Hojjati , Maryam Sadat Mirenayat , Seyed Mansoor Rayegani

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引用次数: 0

Abstract

Introduction

This study aimed to evaluate neuro-musculoskeletal adverse events related to COVID-19 vaccines in Iranian healthcare workers.

Methods

In this cross-sectional survey, a questionnaire was used, including patients’ demographic information, vaccination information, and local, flu-like, and neuro-musculoskeletal side effects of vaccines. All data were extracted and analyzed by SPSS ver.24.

Results

A total of 500 healthcare workers (381 females, and 119 males), with a Mean ± SD age of 38.06 ± 9.22 years old were recruited; 341 subjects (68.2 %) were vaccinated by Sputnik-V vaccine, 95 subjects (19 %) with AstraZeneca, 40 subjects (8 %) with Sinopharm, and 24 (4.8 %) with Baharat COVID-19 vaccine. Out of 500 participants, COVID-19 vaccines' side effects were reported in 428 subjects (85.6 %) including 339 subjects (67.8 %) with local side effects, 342 subjects (68.4 %) subjects with flu-like side effects, 66 subjects (13.2 %) with neurologic, and 291 subjects (58.2 %) with musculoskeletal side effects. Local pain (67.6 %), fatigue (61.2 %), generalized pain (47.8 %), headache (38.8), upper and lower myalgia (44 %, 36 %), and low back pain (26.8 %) were the most common side effects reported by COVID-19 vaccine recipients. There were significant associations between neuro-musculoskeletal side effects with patients’ sex (P = 0.001), categorized age (less and more than 40 years., P = 0.002), and COVID-19 vaccine types (P < 0.001).

Conclusions

Among all the neurological and musculoskeletal side effects, upper limb paresthesia, and upper limb myalgia alongside low back pain were the most frequent respectively. No serious side effects requiring medical attention or hospitalization were reported by participants.

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与 COVID-19 疫苗有关的神经-肌肉-骨骼副作用；对伊朗医护人员的横断面研究

引言本研究旨在评估伊朗医护人员接种 COVID-19 疫苗后出现的神经-肌肉-骨骼不良反应。方法在这项横断面调查中，我们使用了一份调查问卷，其中包括患者的人口统计学信息、疫苗接种信息以及疫苗的局部副作用、流感样副作用和神经-肌肉-骨骼副作用。结果共招募了 500 名医护人员（女性 381 人，男性 119 人），平均（±SD）年龄为 38.06±9.22 岁；其中 341 人（68.2%）接种了 Sputnik-V 疫苗，95 人（19%）接种了阿斯利康疫苗，40 人（8%）接种了国药集团疫苗，24 人（4.8%）接种了巴哈拉特 COVID-19 疫苗。在 500 名参与者中，428 名受试者（85.6%）报告了 COVID-19 疫苗的副作用，其中 339 名受试者（67.8%）有局部副作用，342 名受试者（68.4%）有流感样副作用，66 名受试者（13.2%）有神经系统副作用，291 名受试者（58.2%）有肌肉骨骼副作用。局部疼痛（67.6%）、疲劳（61.2%）、全身疼痛（47.8%）、头痛（38.8%）、上下肌痛（44%、36%）和腰痛（26.8%）是 COVID-19 疫苗接种者报告的最常见副作用。结论在所有神经和肌肉骨骼副作用中，上肢麻痹、上肢肌痛和腰痛分别是最常见的副作用。参与者没有报告需要就医或住院治疗的严重副作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Epidemiology and Global Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-

CiteScore

4.60

自引率

7.70%

发文量

218

审稿时长

66 days

期刊介绍： Clinical Epidemiology and Global Health (CEGH) is a multidisciplinary journal and it is published four times (March, June, September, December) a year. The mandate of CEGH is to promote articles on clinical epidemiology with focus on developing countries in the context of global health. We also accept articles from other countries. It publishes original research work across all disciplines of medicine and allied sciences, related to clinical epidemiology and global health. The journal publishes Original articles, Review articles, Evidence Summaries, Letters to the Editor. All articles published in CEGH are peer-reviewed and published online for immediate access and citation.