{"title":"Bright compact ultrabroadband source by orthogonal laser-sustained plasma","authors":"Zhaojiang Shi, Shichao Yang, He Hu, Haodong Lei, Zhaohua Yang, Xia Yu","doi":"10.1038/s41377-024-01602-2","DOIUrl":null,"url":null,"abstract":"<p>Laser-sustained plasma (LSP) source featuring high brightness and broadband spectral coverage is found to be powerful in various fields of scientific and industrial applications. However, the fundamental limit of low conversion efficiency constrains the system compactness and widespread applications of such broadband light sources. In this paper, we propose an innovative orthogonal LSP to break through the conversion efficiency limitation. Driven by the elevated conversion efficiency from absorbed laser power to ultraviolet (UV) emission, a compact broadband source (250–1650 nm) with UV spectral radiance exceeding 210 <span>\\({mW}/({{mm}}^{2}\\,\\cdot\\, {sr}\\,\\cdot\\, {nm})\\)</span> is achieved with >100 W pump laser. With the plot of a two-dimensional refractive index model, we report an important conceptual advance that the orthogonal design eliminates the influence of the negative lensing effect on laser power density. Experimental results unambiguously demonstrate that we achieve a bright compact UV-VIS-NIR source with negligible thermal loss and the highest conversion efficiency to our knowledge. Significant enhancement of 4 dB contrast-to-noise ratio (CNR) in spectral single-pixel imaging has been demonstrated using the proposed ultrabroadband source. By establishing the quantitative link between pumping optics design and plasma absorption, this work presents a compact broadband source that combines superior conversion efficiency and unprecedented brightness, which is essential to high-speed inspection and spectroscopy applications.</p>","PeriodicalId":20,"journal":{"name":"ACS Medicinal Chemistry Letters","volume":"5 1","pages":""},"PeriodicalIF":3.5000,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"ACS Medicinal Chemistry Letters","FirstCategoryId":"1089","ListUrlMain":"https://doi.org/10.1038/s41377-024-01602-2","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, MEDICINAL","Score":null,"Total":0}
引用次数: 0
Abstract
Laser-sustained plasma (LSP) source featuring high brightness and broadband spectral coverage is found to be powerful in various fields of scientific and industrial applications. However, the fundamental limit of low conversion efficiency constrains the system compactness and widespread applications of such broadband light sources. In this paper, we propose an innovative orthogonal LSP to break through the conversion efficiency limitation. Driven by the elevated conversion efficiency from absorbed laser power to ultraviolet (UV) emission, a compact broadband source (250–1650 nm) with UV spectral radiance exceeding 210 \({mW}/({{mm}}^{2}\,\cdot\, {sr}\,\cdot\, {nm})\) is achieved with >100 W pump laser. With the plot of a two-dimensional refractive index model, we report an important conceptual advance that the orthogonal design eliminates the influence of the negative lensing effect on laser power density. Experimental results unambiguously demonstrate that we achieve a bright compact UV-VIS-NIR source with negligible thermal loss and the highest conversion efficiency to our knowledge. Significant enhancement of 4 dB contrast-to-noise ratio (CNR) in spectral single-pixel imaging has been demonstrated using the proposed ultrabroadband source. By establishing the quantitative link between pumping optics design and plasma absorption, this work presents a compact broadband source that combines superior conversion efficiency and unprecedented brightness, which is essential to high-speed inspection and spectroscopy applications.
期刊介绍:
ACS Medicinal Chemistry Letters is interested in receiving manuscripts that discuss various aspects of medicinal chemistry. The journal will publish studies that pertain to a broad range of subject matter, including compound design and optimization, biological evaluation, drug delivery, imaging agents, and pharmacology of both small and large bioactive molecules. Specific areas include but are not limited to:
Identification, synthesis, and optimization of lead biologically active molecules and drugs (small molecules and biologics)
Biological characterization of new molecular entities in the context of drug discovery
Computational, cheminformatics, and structural studies for the identification or SAR analysis of bioactive molecules, ligands and their targets, etc.
Novel and improved methodologies, including radiation biochemistry, with broad application to medicinal chemistry
Discovery technologies for biologically active molecules from both synthetic and natural (plant and other) sources
Pharmacokinetic/pharmacodynamic studies that address mechanisms underlying drug disposition and response
Pharmacogenetic and pharmacogenomic studies used to enhance drug design and the translation of medicinal chemistry into the clinic
Mechanistic drug metabolism and regulation of metabolic enzyme gene expression
Chemistry patents relevant to the medicinal chemistry field.