Optimal strategies for exercise intervention in older people diabetic patients: The impacts of intensity, form, and frequency on glycemic control

IF 3.5 3区医学 Q2 GERIATRICS & GERONTOLOGY

Archives of gerontology and geriatrics Pub Date : 2024-09-14 DOI:10.1016/j.archger.2024.105621

Xueru Yan , Yujuan Lu , Haoda Zhang , Chen Zhu , Lan Tian , Jishuai Chen , Enpeng He , Yingying Li

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引用次数: 0

Abstract

Objective

This study aims to investigate the optimal exercise intensity, type, and weekly duration for improving glycated haemoglobin (HbA1c) and fasting blood glucose (FBG) levels in older people individuals with diabetes.

Materials and Methods

PubMed, EMBASE, Web of Science and other databases were searched to identify randomised controlled trials (RCTs) starting from January 2000 to February 2024 that reported improved effects on fasting glucose and glycated haemoglobin after different exercises in middle-aged and elderly diabetic patients. Meta-analyses Review Manager V.5.3 was used.

Results

Meta-analysis showed that moderate- and high-intensity exercise had a significant effect on HbA1c levels, with a mean difference (MD) of -0.34 (95 % CI: -0.44 ∼ -0.24, p < 0.01) for moderate-intensity exercise and -0.54 (95 % CI: -0.78 ∼ -0.3, p < 0.001) for high-intensity exercise.. Both moderate-intensity and high-intensity exercise demonstrated statistical significance in lowering fasting blood glucose levels (p < 0.001). Additionally, there was no significant difference between aerobic and resistance exercise forms (p= 0.72). Furthermore, for reducing HbA1c levels, engageing in weekly exercise for at least 2.5 hours showed a MD of-0.44(95 % CI:-0.63∼0.25;p<0.001).

Conclusions

In summary, in terms of exercise intensity, medium and high-intensity exercise can significantly reduce HbA1c and FBG levels in middle-aged and older people diabetic patients; in terms of exercise form, the effects of different exercise forms within medium and high-intensity on HbA1c and FBG are not statistically significant; and in terms of exercise time, in moderate-intensity aerobic exercise, older people exercising for more than 2.5 h per week are more beneficial.

查看原文本刊更多论文

老年糖尿病患者运动干预的最佳策略：运动强度、形式和频率对血糖控制的影响

本研究旨在探讨改善中老年糖尿病患者糖化血红蛋白（HbA1c）和空腹血糖（FBG）水平的最佳运动强度、类型和每周持续时间。材料与方法检索了PubMed、EMBASE、Web of Science和其他数据库，以确定2000年1月至2024年2月期间报道了不同运动对中老年糖尿病患者空腹血糖和糖化血红蛋白改善效果的随机对照试验（RCT）。结果表明，中等强度和高强度运动对 HbA1c 水平有显著影响，中等强度运动的平均差（MD）为 -0.34 (95 % CI: -0.44 ∼ -0.24, p < 0.01)，高强度运动的平均差（MD）为 -0.54 (95 % CI: -0.78 ∼ -0.3, p < 0.001)。中强度和高强度运动在降低空腹血糖水平方面均具有统计学意义（p < 0.001）。此外，有氧运动和阻力运动之间没有显著差异（p= 0.72）。此外，在降低 HbA1c 水平方面，每周锻炼至少 2.5 小时的 MD 值为-0.44（95 % CI：-0.63∼0.25；p<0.001）。结论综上所述，就运动强度而言，中、高强度运动可显著降低中老年糖尿病患者的HbA1c和FBG水平；就运动形式而言，中、高强度内不同运动形式对HbA1c和FBG的影响无统计学意义；就运动时间而言，在中等强度有氧运动中，每周运动2.5小时以上的中老年人更有益。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Archives of gerontology and geriatrics 医学-老年医学

CiteScore

7.30

自引率

5.00%

发文量

198

审稿时长

16 days

期刊介绍： Archives of Gerontology and Geriatrics provides a medium for the publication of papers from the fields of experimental gerontology and clinical and social geriatrics. The principal aim of the journal is to facilitate the exchange of information between specialists in these three fields of gerontological research. Experimental papers dealing with the basic mechanisms of aging at molecular, cellular, tissue or organ levels will be published. Clinical papers will be accepted if they provide sufficiently new information or are of fundamental importance for the knowledge of human aging. Purely descriptive clinical papers will be accepted only if the results permit further interpretation. Papers dealing with anti-aging pharmacological preparations in humans are welcome. Papers on the social aspects of geriatrics will be accepted if they are of general interest regarding the epidemiology of aging and the efficiency and working methods of the social organizations for the health care of the elderly.