Rave gone wrong: MDMA- induced medical emergency at electrical daisy carnival. A case report

Q1 Environmental Science
Charissa Alo , Mutsumi J. Kioka
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引用次数: 0

Abstract

3, 4-methylenedioxyamphetamine (MDMA) has gained significance over the years, especially at rave festivals, as a recreational drug for its noted effects in mood enhancement and autonomic stimulation. While these effects have been noted, severe adverse outcomes, and even death, following the ingestion of MDMA have been recorded.
We present a 35-year-old male who ingested the drug at the Electric Daisy Carnival (EDC), the largest electronic dance music festival in North America as of 2024 [1]. Every year, many young adults are brought to local hospitals from the festival for drug overdoses, hyperthermia, and dehydration. At the festival, the patient was witnessed to have a seizure, presented with altered mental status and deemed hyperthermic at 109 degrees Fahrenheit. For these reasons, he was rapidly intubated and submerged in an ice bath at the festival’s medical tent. At the county hospital, the patient was diagnosed with multiorgan failure, cerebrovascular ischemia, and coagulopathy. He received life-saving treatment such as continuous renal replacement therapy as well as intubation for acute hypoxemic respiratory failure. MRI of the brain showed central- embolic infarcts and the patient was closely monitored in the intensive care unit (ICU) for eight days. After twenty days of inpatient treatment, the patient was discharged. He was discharged with his mental status at baseline and without gross neurologic deficits. A permacath was placed for hemodialysis to be continued outpatient.
This case report highlights the importance of prompt medical management which can be crucial for patient survival following a life-threatening overdose with MDMA. It also exemplifies the need for increasing social awareness regarding the severe and detrimental outcomes an MDMA overdose can cause as this drug continues to be widely used in the setting of rave and music festivals.
狂欢出错:电子雏菊狂欢节上由摇头丸诱发的医疗紧急情况。病例报告
3,4-亚甲二氧基苯丙胺(MDMA)作为一种娱乐性毒品,因其在增强情绪和刺激自律神经方面的显著效果,多年来在狂欢节上尤其受到人们的重视。我们介绍的是一名 35 岁的男性,他在 "电子雏菊嘉年华"(Electric Daisy Carnival,简称 EDC)上摄入了这种药物,EDC 是截至 2024 年北美最大的电子舞曲音乐节[1]。每年都有许多年轻人因药物过量、高热和脱水而从音乐节被送往当地医院。在音乐节上,有人目睹患者癫痫发作,出现精神状态改变,并被认为是华氏 109 度的高热。由于这些原因,他被迅速插管并浸泡在节日医疗帐篷的冰水中。在县医院,病人被诊断为多器官衰竭、脑血管缺血和凝血功能障碍。他接受了抢救治疗,如持续肾脏替代疗法以及急性低氧呼吸衰竭插管治疗。脑部核磁共振成像显示存在中心性栓塞性梗死,患者在重症监护室(ICU)接受了八天的密切监护。经过二十天的住院治疗后,患者康复出院。出院时,患者的精神状态保持在基线水平,没有出现严重的神经功能缺损。本病例报告强调了及时医疗处理的重要性,这对于亚甲二氧基甲基苯丙胺过量危及生命后患者的存活至关重要。本病例报告强调了及时救治的重要性,这对亚甲二氧基甲基苯丙胺过量危及生命的患者的存活至关重要。本病例报告还说明,随着亚甲二氧基甲基苯丙胺继续在狂欢和音乐节中广泛使用,有必要提高社会对亚甲二氧基甲基苯丙胺过量可能导致严重危害后果的认识。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Toxicology Reports
Toxicology Reports Environmental Science-Health, Toxicology and Mutagenesis
CiteScore
7.60
自引率
0.00%
发文量
228
审稿时长
11 weeks
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