Association between sleep disorder and depression in stroke in the National Health and Nutrition Examination Surveys (NHANES) 2005 to 2014

IF 3.8 2区医学 Q1 CLINICAL NEUROLOGY

Sleep medicine Pub Date : 2024-09-19 DOI:10.1016/j.sleep.2024.09.021

Qinghua Wen , Juan Li , Simin Li , Xiaoyue Wang , Huanhuan Zhu , Fengyin Zhang

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引用次数: 0

Abstract

Background

To investigate the association between sleep disorder and depression in stroke population using data from the National Health and Nutrition Examination Surveys (NHANES) conducted between 2005 and 2014.

Methods

Participants included stroke population who reported on sleep disorder and completed the Patient Health Questionnaire-9 (PHQ-9) to assess depressive symptom. Sleep disorder was self-reported and categorized dichotomously. Multivariate logistic regression, subgroup analysis, receiver operating characteristic curve (ROC) and restricted cubic spline (RCS) were used to explore the association between sleep disorder and depression.

Results

The final sample included 566 stroke survivors (weighted n = 3,326,625). Multivariate logistic regression analysis confirmed that sleep disorder was independently associated with an increased risk of depression even after adjusting for potential confounders (OR = 2.616, 95 % CI: 2.561 to 2.599, P < 0.0001). Subgroup analysis indicated that this association was particularly strong among female stroke population (OR = 5.515). Sleep disorder as a significant predictor of depression, while the relationship between sleep time and depression is characterized by non-linearity.

Conclusions

Sleep disorder is significantly associated with an increased risk of depression in stroke. This relationship remains robust across various sociodemographic and lifestyle factors, highlighting the need for integrated interventions targeting both sleep and mood disturbances in stroke care.

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2005 年至 2014 年美国国家健康与营养调查（NHANES）中中风患者睡眠障碍与抑郁之间的关系

背景目的利用 2005 年至 2014 年间进行的美国国家健康与营养调查（NHANES）的数据，研究中风人群中睡眠障碍与抑郁症之间的关系。方法参与者包括报告睡眠障碍并完成患者健康问卷-9（PHQ-9）以评估抑郁症状的中风人群。睡眠障碍由患者自我报告，并以二分法进行分类。采用多变量逻辑回归、亚组分析、接收器操作特征曲线（ROC）和限制性立方样条曲线（RCS）来探讨睡眠障碍与抑郁症之间的关系。多变量逻辑回归分析证实，即使调整了潜在的混杂因素（OR = 2.616，95 % CI：2.561 至 2.599，P < 0.0001），睡眠障碍仍与抑郁风险增加有独立关联。亚组分析表明，这种关联在女性卒中人群中尤为明显（OR = 5.515）。睡眠障碍是抑郁的重要预测因素，而睡眠时间与抑郁之间的关系具有非线性特征。这种关系在各种社会人口和生活方式因素的影响下仍然保持稳定，这突出表明在中风护理中需要针对睡眠和情绪障碍采取综合干预措施。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Sleep medicine 医学-临床神经学

CiteScore

8.40

自引率

6.20%

发文量

1060

审稿时长

49 days

期刊介绍： Sleep Medicine aims to be a journal no one involved in clinical sleep medicine can do without. A journal primarily focussing on the human aspects of sleep, integrating the various disciplines that are involved in sleep medicine: neurology, clinical neurophysiology, internal medicine (particularly pulmonology and cardiology), psychology, psychiatry, sleep technology, pediatrics, neurosurgery, otorhinolaryngology, and dentistry. The journal publishes the following types of articles: Reviews (also intended as a way to bridge the gap between basic sleep research and clinical relevance); Original Research Articles; Full-length articles; Brief communications; Controversies; Case reports; Letters to the Editor; Journal search and commentaries; Book reviews; Meeting announcements; Listing of relevant organisations plus web sites.