Late meningitis and a nonabsorbable stent in recurrent Rathke's cleft cyst: illustrative case.

Simona Serioli, Vincenzo Mastropasqua, Giorgia De Rosa, Romina Ebrahimian, Pierpaolo Mattogno, Mario Rigante, Simona Gaudino, Salvatore Maria Corsello, Liverana Lauretti, Rita Murri, Marco Gessi, Alessandro Olivi, Francesco Doglietto
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Abstract

Background: The management of recurrent Rathke's cleft cysts (RCCs) remains challenging. The off-label application of steroid-eluting bioabsorbable or nonabsorbable intracystic stents has been recently described. Early outcomes and complications of this treatment have been described as well, but long-term data are lacking.

Observations: A 31-year-old woman who had undergone 3 prior transsphenoidal surgeries for recurrent RCC at other institutions was admitted for methicillin-susceptible Staphylococcus aureus meningitis. Five years earlier, a nonabsorbable stent had been placed in the cyst using a microsurgical transsphenoidal approach. RCC recurrence had been radiologically evident after 2 years but was clinically asymptomatic. Acute cerebrospinal fluid leakage and other causes of meningitis were ruled out; the stent was occluded. After antibiotic therapy and resolution of the meningitis, the patient underwent endoscopic removal of the catheter, excision of the cyst, and reconstruction with a nasoseptal flap. At the 18-month follow-up, she remained neurologically intact, under replacement therapy, and with no signs of recurrence.

Lessons: The authors report the first case of late meningitis due to a nonabsorbable stent positioned for the treatment of a recurrent RCC. Currently, data on the long-term outcomes, failure rates, and complications of stents for RCC are limited. https://thejns.org/doi/10.3171/CASE2477.

复发性拉斯克裂囊肿的晚期脑膜炎和不可吸收支架:示例病例。
背景:复发性拉氏裂隙囊肿(RCC)的治疗仍然具有挑战性。最近有学者在标签外应用类固醇洗脱生物可吸收或不可吸收囊内支架。这种治疗方法的早期疗效和并发症也有描述,但缺乏长期数据:一名 31 岁的女性曾因复发性 RCC 在其他机构接受过 3 次经椎体手术,因甲氧西林易感金黄色葡萄球菌脑膜炎入院。五年前,该患者曾使用显微外科经蝶窦方法在囊肿内放置了一个不可吸收的支架。两年后,RCC复发在影像学上很明显,但临床上无症状。排除了急性脑脊液漏和其他脑膜炎病因,支架已被堵塞。经过抗生素治疗和脑膜炎缓解后,患者接受了内窥镜导管移除、囊肿切除和鼻隔皮瓣重建手术。在 18 个月的随访中,她的神经系统仍然完好,正在接受替代疗法,没有复发迹象:启示:作者报告了首例因使用不可吸收支架治疗复发性 RCC 而导致晚期脑膜炎的病例。目前,有关支架治疗 RCC 的长期效果、失败率和并发症的数据还很有限。https://thejns.org/doi/10.3171/CASE2477。
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