{"title":"The Effect of Probiotics and Microbiota on Nervous System and Mental Illnesses.","authors":"Hadi Hossainpour, Salman Khazaei, Hassan Mahmoudi","doi":"10.2174/0118715249315760240905043415","DOIUrl":null,"url":null,"abstract":"<p><p>The microbiota that inhabits the gastrointestinal tract has been linked to various gastrointestinal and non-gastrointestinal disorders. Scientists have been studying how the bacteria in our intestines have an effect on our brain and nervous system. This connection is called the \"microbiota- gut-brain axis\". Given the capacity of probiotics, which are live non-pathogenic microorganisms, to reinstate the normal microbial population within the host and confer advantages, their potential impact has been subjected to scrutiny with regard to neurological and mental conditions. Material sourced for this review included peer-reviewed literature annotated in the PubMed, Web of Science, Scopus, and Google Scholar databases. The result has indicated the integration of probiotics into a child's diet to enhance the neuro-behavioral symptoms. Notwithstanding this, the current data set has been found to be insufficient and inconclusive. The potential utility of probiotics for the prevention or treatment of neurologic and mental disorders has become a subject of substantial interest.</p>","PeriodicalId":93930,"journal":{"name":"Central nervous system agents in medicinal chemistry","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Central nervous system agents in medicinal chemistry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/0118715249315760240905043415","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The microbiota that inhabits the gastrointestinal tract has been linked to various gastrointestinal and non-gastrointestinal disorders. Scientists have been studying how the bacteria in our intestines have an effect on our brain and nervous system. This connection is called the "microbiota- gut-brain axis". Given the capacity of probiotics, which are live non-pathogenic microorganisms, to reinstate the normal microbial population within the host and confer advantages, their potential impact has been subjected to scrutiny with regard to neurological and mental conditions. Material sourced for this review included peer-reviewed literature annotated in the PubMed, Web of Science, Scopus, and Google Scholar databases. The result has indicated the integration of probiotics into a child's diet to enhance the neuro-behavioral symptoms. Notwithstanding this, the current data set has been found to be insufficient and inconclusive. The potential utility of probiotics for the prevention or treatment of neurologic and mental disorders has become a subject of substantial interest.
居住在胃肠道中的微生物群与各种胃肠道和非胃肠道疾病有关。科学家一直在研究肠道中的细菌如何影响我们的大脑和神经系统。这种联系被称为 "微生物群-肠道-大脑轴"。益生菌是一种活的非致病性微生物,能够恢复宿主体内正常的微生物种群并带来益处,因此益生菌对神经和精神疾病的潜在影响受到了严格的审查。本综述的资料来源包括在 PubMed、Web of Science、Scopus 和 Google Scholar 数据库中注释的同行评审文献。结果表明,在儿童饮食中添加益生菌可改善神经行为症状。尽管如此,目前的数据集还不够充分,没有定论。益生菌在预防或治疗神经和精神疾病方面的潜在作用已成为一个备受关注的话题。