Non-contrast-enhanced MR-angiography of Extracranial Arteries in Acute Ischemic Stroke at 1.5 Tesla Using Relaxation-Enhanced Angiography Without Contrast and Triggering (REACT).

IF 2.4 3区医学 Q2 CLINICAL NEUROLOGY

Clinical Neuroradiology Pub Date : 2024-09-24 DOI:10.1007/s00062-024-01458-4

Jan P Janssen, Sarah Rose, Kenan Kaya, Robert Terzis, Robert Hahnfeldt, Roman J Gertz, Lukas Goertz, Andra-Iza Iuga, Jan-Peter Grunz, Christoph Kabbasch, Philip Rauen, Thorsten Persigehl, Kilian Weiss, Jan Borggrefe, Lenhard Pennig, Carsten Gietzen

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引用次数: 0

Abstract

Purpose: To evaluate a novel flow-independent sequence (Relaxation-Enhanced Angiography without Contrast and Triggering (REACT)) for imaging of the extracranial arteries in acute ischemic stroke (AIS) at 1.5 T.

Methods: This retrospective single-center study included 47 AIS patients who received REACT (scan time: 3:01 min) and contrast-enhanced MRA (CE-MRA) of the extracranial arteries at 1.5 T in clinical routine. Two radiologists assessed scans for proximal internal carotid artery (ICA) stenosis, stated their diagnostic confidence and rated the image quality of cervical arteries, impact of artifacts and image noise. Apparent signal- and contrast-to-noise ratios (aSNR/aCNR) were measured for the common carotid artery and ICA.

Results: REACT achieved a sensitivity of 95.0% and a specificity of 97.3% for ICA stenoses in high agreement with CE-MRA (κ = 0.83) with equal diagnostic confidence (p = 0.22). Image quality was rated higher for CE-MRA at the aortic arch (p = 0.002) and vertebral arteries (p < 0.001), whereas REACT provided superior results for the extracranial ICA (p = 0.008). Both sequences were only slightly affected by artifacts (p = 0.60), while image noise was more pronounced in CE-MRA (p < 0.001) in line with higher aSNR (p < 0.001) and aCNR (p < 0.001) values in REACT for all vessels.

Conclusion: Given its good diagnostic performance while yielding comparable image quality and scan time to CE-MRA, REACT may be suitable for the imaging of the extracranial arteries in acute ischemic stroke at 1.5 T.

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在 1.5 特斯拉下使用无对比剂和触发的弛豫增强血管造影（REACT）对急性缺血性卒中的颅外动脉进行非对比剂增强 MR 血管造影。

目的：评估在 1.5 T 下对急性缺血性卒中（AIS）颅内外动脉成像的新型血流无关序列（无对比度和触发的弛豫增强血管造影（REACT））：这项回顾性单中心研究纳入了 47 名 AIS 患者，他们在临床常规中接受了 REACT（扫描时间：3:01 分钟）和 1.5 T 颅外动脉对比增强 MRA（CE-MRA）。两名放射科医生对扫描结果进行了评估，以确定是否存在近端颈内动脉（ICA）狭窄，他们还对颈动脉的图像质量、伪影的影响和图像噪声进行了评分。测量了颈总动脉和ICA的显像信噪比和对比信噪比（aSNR/aCNR）：REACT 对 ICA 狭窄的灵敏度为 95.0%，特异度为 97.3%，与 CE-MRA 高度一致（κ = 0.83），诊断可信度相同（p = 0.22）。主动脉弓（p = 0.002）和椎动脉（p 结论：CE-MRA 的图像质量评分更高：REACT具有良好的诊断性能，同时图像质量和扫描时间与CE-MRA相当，因此可能适合在1.5 T下对急性缺血性卒中的颅外动脉进行成像。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Neuroradiology CLINICAL NEUROLOGY-RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

CiteScore

5.00

自引率

3.60%

发文量

106

审稿时长

>12 weeks

期刊介绍： Clinical Neuroradiology provides current information, original contributions, and reviews in the field of neuroradiology. An interdisciplinary approach is accomplished by diagnostic and therapeutic contributions related to associated subjects. The international coverage and relevance of the journal is underlined by its being the official journal of the German, Swiss, and Austrian Societies of Neuroradiology.