[Allergic contact dermatitis due to Furacin®].

Lucía Moreno-Lozano, Teresa de Aramburu-Mera, Carmen Bermúdez-Hormigo
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Abstract

Background: Allergic sensitization to topical antimicrobial treatments is a well-known problem. Furacin® is one of the most widely used in our environment. It contains 0.2% nitrofurazone and polyethylene glycol (PEG) as a vehicle.

Case report: 57-year-old male with no history of interest. He presented skin rash, blisters, and serous exudate 2-3 days after starting treatment with Furacin® (applied to an infected skin wound). Epicutaneous tests were performed with a true test battery, nitrofurantoin 1% in petrolatum, PEG15000 and 4000 1% in petrolatum, pure PEG 400, PEG monomethyl ether 350 1% in water. Positive result at 96 hours for nitrofurantoin.

Conclusion: Nitrofurazone is widely used as a topical antibiotic because of its bactericidal spectrum. It (including its excipients) should be considered in case of adverse reactions after application.

[Furacin®引起的过敏性接触性皮炎]。
背景:外用抗菌药过敏是一个众所周知的问题。呋喃西林®是在我们的环境中使用最广泛的药物之一。它含有 0.2% 的硝基呋喃唑酮和聚乙二醇(PEG)作为载体:57 岁男性,无相关病史。病例报告:57 岁男性,无相关病史,在开始使用 Furacin®(用于感染性皮肤伤口)治疗 2-3 天后出现皮疹、水疱和浆液性渗出物。使用真正的测试电池、1% 硝基呋喃妥因(含凡士林)、1% PEG15000 和 4000(含凡士林)、纯 PEG 400、1% PEG 单甲醚 350(含水)进行了皮肤测试。96 小时后,硝基呋喃妥因呈阳性结果:结论:硝基呋喃唑酮因其杀菌谱广而被广泛用作局部抗生素。结论:硝基呋喃唑酮因其杀菌谱广而被广泛用作外用抗生素,在使用后出现不良反应时应考虑使用硝基呋喃唑酮(包括其辅料)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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