Bell's palsy and COVID-19: A cohort study with historical rate comparison

Natalia Arango , María Jesús Rojas-Lechuga , Jiwei Chen , Francisco Larrosa , Berta Alegre , Isabel Vilaseca
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Abstract

Introduction

During the SARS-CoV-2 pandemic, immune-mediated neurological events have been described in patients vaccinated against the virus or who have overcome the disease. Among these events is Idiopathic peripheral facial palsy or Bell’s palsy.

Objectives

To study the incidence of Bell's Palsy in the ENT emergency department of a tertiary hospital in Catalonia during the SARS-CoV-2 pandemic.

Methods

Retrospective historical cohort comparison study of patients diagnosed with Bell's palsy between January 2018 and December 2021. Crude incidence rates were calculated as the total number of events divided by person time at risk per 100.000 person-years. Observed (2020, 2021) and historical (2018, 2019) rates were compared using standardized incidence rates with corresponding 95% confidence intervals.

Results

Of the total number of ENT emergency department visits from 2018 to 2021 (22.658), there were 247 cases of Bell's palsy. The incidence rate of Bell's palsy in the pre-pandemic group was 12,2 and 10,9 per 100.000 person-years for 2018 and 2019, respectively. The 2020 standardized incidence rate of Bell's palsy was 0,70 [95% CI 0,49–1,01] and 1,25 [95% CI 0,93–1,67] for 2021. No significant differences were evident between the two groups.

Conclusion

In our cohort, no association was found between vaccination or COVID-19 infection and the development of Bell's Palsy.
贝尔氏麻痹与 COVID-19:一项与历史发病率比较的队列研究。
简介在SARS-CoV-2大流行期间,接种过该病毒疫苗或战胜该疾病的患者中出现了免疫介导的神经系统事件。其中包括特发性周围性面瘫或贝尔氏麻痹:研究加泰罗尼亚一家三级医院耳鼻喉科急诊室在 SARS-CoV-2 大流行期间贝尔麻痹的发病率:对2018年1月至2021年12月期间确诊的贝尔氏麻痹患者进行回顾性历史队列比较研究。粗发病率按每 10 万人年的事件总数除以风险时间计算。使用标准化发病率和相应的 95% 置信区间对观察率(2020、2021 年)和历史发病率(2018、2019 年)进行比较:在2018年至2021年耳鼻喉科急诊就诊总人数(22.658)中,有247例贝尔氏麻痹。2018年和2019年,大流行前组的贝尔氏麻痹发病率分别为每10万人年12.2例和10.9例。2020 年贝尔氏麻痹的标准化发病率为 0,70 [95% CI 0,49 -1,01] ,2021 年为 1,25 [95% CI 0,93 至 1,67]。两组之间没有明显差异:在我们的队列中,没有发现疫苗接种或 COVID-19 感染与贝尔氏麻痹的发生有任何关联。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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