Donor hepatectomy time and liver transplantation outcomes: An opportunity that cannot be dismissed.

Francisca Gonzalez Cohens, Fernando M Gonzalez
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引用次数: 0

Abstract

The probability of developing primary dysfunction (PD) is a function of the probability of ischemia/reperfusion (I/R) injury. The probability of I/R injury in turn, is a function of several donor and transplantation process variables, among which is ischemia time. Custodio et al studied the duration of a special type of warm ischemia and showed, contrary to what is known, that a longer duration is not statistically different from a shorter one in PD development. This finding opens the door to the unforeseen opportunity of training fellows in performing hepatectomies, since the duration will not jeopardize liver transplant outcomes, albeit with some precautions.

供体肝切除时间与肝移植结果:不容忽视的机遇
发生原发性功能障碍(PD)的概率是缺血/再灌注(I/R)损伤概率的函数。而缺血/再灌注损伤的概率又是多个供体和移植过程变量的函数,其中包括缺血时间。Custodio 等人研究了一种特殊类型的温缺血持续时间,结果表明,与已知情况相反,缺血持续时间长与短在统计学上并无差异。这一发现为培训研究员进行肝切除术提供了不可预见的机会,因为尽管有一些预防措施,但持续时间不会危及肝移植结果。
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CiteScore
3.50
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