Atopic Dermatitis (Eczema) Guidelines 2023: Highlights

IF 8.2 1区医学 Q1 ALLERGY

Journal of Allergy and Clinical Immunology-In Practice Pub Date : 2024-11-01 DOI:10.1016/j.jaip.2024.08.052

Anna De Benedetto MD , Mark Boguniewicz MD , Peck Y. Ong MD , Derek K. Chu MD, PhD , Lynda C. Schneider MD

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引用次数: 0

Abstract

Atopic dermatitis is a common chronic inflammatory skin disorder, with a complex pathogenesis. It is characterized by eczematous skin lesions, pruritus, and recurrent skin infections and has a negative impact on patients’ and caregivers’ quality of life. The American Academy of Allergy, Asthma & Immunology/American College of Allergy, Asthma and Immunology Joint Task Force Atopic Dermatitis Guideline Panel recently released updated AD guidelines. This guideline focuses on addressing clinical questions using trustworthy guideline development standards, including mitigating the potential influence of financial and nonfinancial conflicts of interest, and Grading of Recommendations Assessment, Development, and Evaluation methodology. A multidisciplinary panel used systematic reviews and meta-analyses to inform specific recommendations addressing optimal use of topical treatments, dilute bleach bath, dietary avoidance/elimination, allergen immunotherapy, and systemic treatments. The comprehensive recommendations, emphasizing the third principle of evidence-based medicine—that evidence alone is never enough, and that patient values and preferences must be carefully considered when determining optimal treatments for patients and populations—provide a framework to support clinicians in selecting an optimal treatment plan for each patient. This review provides an overview of the guideline and discusses how those recommendations relate to current practice.

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特应性皮炎（湿疹）指南 2023》：亮点。

特应性皮炎（AD）是最常见的慢性炎症性皮肤病之一，发病机制复杂。特应性皮炎以皮肤湿疹、瘙痒和反复皮肤感染为特征，对患者（和护理人员）的生活质量有负面影响。美国过敏、哮喘和免疫学学会（AAAAI）/美国过敏、哮喘和免疫学学院（ACAAI）特应性皮炎联合工作组（JTF）指南小组最近发布了最新的特应性皮炎指南。该指南的重点是采用值得信赖的指南制定标准（包括减轻经济和非经济利益冲突的潜在影响）和 GRADE 方法解决临床问题。一个多学科小组利用系统综述和荟萃分析，针对以下方面提出了具体建议：(1) 局部治疗；(2) 稀释漂白浴；(3) 避免/消除饮食；(4) 过敏原免疫疗法；(5) 全身治疗。这些全面的建议强调了循证医学的第三条原则--仅有证据是远远不够的；在为患者和人群确定最佳治疗方法时，必须仔细考虑患者的价值观和偏好--为临床医生为每位患者选择最佳治疗方案提供了一个框架。本综述概述了该指南，并讨论了这些建议与当前实践的关系。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Allergy and Clinical Immunology-In Practice ALLERGYIMMUNOLOGY-IMMUNOLOGY

CiteScore

11.10

自引率

9.60%

发文量

683

审稿时长

50 days

期刊介绍： JACI: In Practice is an official publication of the American Academy of Allergy, Asthma & Immunology (AAAAI). It is a companion title to The Journal of Allergy and Clinical Immunology, and it aims to provide timely clinical papers, case reports, and management recommendations to clinical allergists and other physicians dealing with allergic and immunologic diseases in their practice. The mission of JACI: In Practice is to offer valid and impactful information that supports evidence-based clinical decisions in the diagnosis and management of asthma, allergies, immunologic conditions, and related diseases. This journal publishes articles on various conditions treated by allergist-immunologists, including food allergy, respiratory disorders (such as asthma, rhinitis, nasal polyps, sinusitis, cough, ABPA, and hypersensitivity pneumonitis), drug allergy, insect sting allergy, anaphylaxis, dermatologic disorders (such as atopic dermatitis, contact dermatitis, urticaria, angioedema, and HAE), immunodeficiency, autoinflammatory syndromes, eosinophilic disorders, and mast cell disorders. The focus of the journal is on providing cutting-edge clinical information that practitioners can use in their everyday practice or to acquire new knowledge and skills for the benefit of their patients. However, mechanistic or translational studies without immediate or near future clinical relevance, as well as animal studies, are not within the scope of the journal.