Impact of body mass index and waist-to-hip ratio on mortality in middle-aged Koreans: A prospective cohort study based on a Health Examinees study.

IF 2.2 4区医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Epidemiology and Health Pub Date : 2024-09-02 DOI:10.4178/epih.e2024073

Sooyoung Cho, Aesun Shin, Ji-Yeob Choi, Jong-Koo Lee, Daehee Kang

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引用次数: 0

Abstract

Objectives: We aimed to assess the impact of obesity on mortality in middle-aged Koreans using data from a Health Examinees study.

Methods: We used data from the participants who had complete information on body size and gave informed consent for the linkage of their data with the national death certificate data. Cox proportional hazard model was used to estimate the hazard ratios (HRs) and 95% confidence intervals (CIs) of body mass index (BMI) and waist-to-hip ratio (WHR) for all-cause, cardiovascular, and cancer mortality.

Results: A total of 115,961 participants were included in the study. The results showed a U-shaped association between BMI and mortality, indicating that both men and women with BMIs of less than 21 kg/m2 and greater than or equal to 30 kg/m2 are at increased risk. The results showed that men with a BMI of less than 18.5 kg/m² had a significantly higher risk of all-cause mortality (adjusted HR: 2.24 [95% CI: 1.73-2.91]) and cardiovascular mortality (2.27 [1.23-4.20]). Similarly, men with a WHR of less than 0.80 (1.38 [1.08-1.77]), 0.90 to less than 0.95 (1.15 [1.02-1.29]), and greater than or equal to 0.95 (1.28 [1.11-1.47]) showed an increased risk of all-cause mortality. In women, a BMI of less than 18 kg/m² was linked to a higher risk of cardiovascular mortality (2.67 [1.13-6.33]).

Conclusion: Being underweight was associated with an increased risk of mortality in both sexes, and the lowest risk of death was found in men who were slightly overweight with a BMI of 23-25 kg/m2.

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体重指数和腰臀比对韩国中年人死亡率的影响：基于健康体检者研究的前瞻性队列研究。

目的我们旨在利用一项健康体检研究的数据，评估肥胖对韩国中年人死亡率的影响：我们使用的数据来自于拥有完整体型信息并知情同意将其数据与国家死亡证明数据进行关联的参与者。我们使用 Cox 比例危险模型估算了体重指数（BMI）和腰臀比（WHR）对全因、心血管和癌症死亡率的危险比（HRs）和 95% 置信区间（CIs）：共有 115 961 名参与者参与了研究。结果显示，体重指数与死亡率呈 U 型关系，表明体重指数小于 21 kg/m2 和大于或等于 30 kg/m2 的男性和女性的风险都会增加。结果显示，体重指数小于 18.5 kg/m² 的男性全因死亡风险（调整后 HR：2.24 [95% CI：1.73-2.91]）和心血管死亡风险（2.27 [1.23-4.20]）明显更高。同样，WHR 小于 0.80 (1.38 [1.08-1.77])、0.90 至小于 0.95 (1.15 [1.02-1.29])、大于或等于 0.95 (1.28 [1.11-1.47])的男性全因死亡风险增加。在女性中，体重指数小于 18 kg/m² 与较高的心血管死亡风险有关（2.67 [1.13-6.33]）：结论：体重过轻与男女死亡风险增加有关，而体重指数为 23-25 kg/m2 的轻微超重男性的死亡风险最低。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Epidemiology and Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-

CiteScore

6.30

自引率

2.60%

发文量

106

审稿时长

4 weeks

期刊介绍： Epidemiology and Health (epiH) is an electronic journal publishing papers in all areas of epidemiology and public health. It is indexed on PubMed Central and the scope is wide-ranging: including descriptive, analytical and molecular epidemiology; primary preventive measures; screening approaches and secondary prevention; clinical epidemiology; and all aspects of communicable and non-communicable diseases prevention. The epiH publishes original research, and also welcomes review articles and meta-analyses, cohort profiles and data profiles, epidemic and case investigations, descriptions and applications of new methods, and discussions of research theory or public health policy. We give special consideration to papers from developing countries.