Investigation of the biological activity and toxicity of bioactive silver nanoparticles synthesized via Vitex agnus-castus seed extract on honey bees.

IF 1.8 3区农林科学 Q2 VETERINARY SCIENCES

Veterinary Research Communications Pub Date : 2024-12-01 Epub Date: 2024-09-21 DOI:10.1007/s11259-024-10550-6

Seda Ekici, Ogun Bozkaya, Sedat Sevin, Babur Erdem, Okan Can Arslan, Ozge Özgenç Cinar, Esra Bozkaya, Husamettin Ekici

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引用次数: 0

Abstract

In this study, silver nanoparticles (AgNPs) coated with bioactive molecules were synthesized via Vitex agnus-castus L. (VAC) seed extract (VAC/AgNPs). The synthesized VAC/AgNPs were characterized by surface plasmon resonance (SPR) ultraviolet-visible region spectroscopy (UV-Vis). The hydrodynamic size and surface charge analysis of the particles were measured with a Zeta sizer. The results of UV-Vis and Zeta analysis revealed that AgNPs were synthesized, the size distribution was nanoscale, and the solution was stable. The effects of the synthesized VAC/AgNPs and aqueous extract of VAC seeds on honeybees were investigated by means of lifespan test and histopathological analysis. It was determined that both VAC seed extract and VAC/AgNPs were non-toxic to honeybees at certain doses, positively affected their life span and contributed to their longevity in the life span test. Furthermore, no adverse effects were detected in terms of intestinal health in histopathological examinations. Therefore, VAC/AgNPs are considered to be a promising bioactive agent for honeybees.

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通过荆芥种子提取物合成的生物活性银纳米粒子对蜜蜂的生物活性和毒性研究。

本研究通过荆芥（VAC）种子提取物合成了包覆生物活性分子的银纳米粒子（AgNPs）（VAC/AgNPs）。通过表面等离子体共振（SPR）紫外可见光谱（UV-Vis）对合成的 VAC/AgNPs 进行了表征。用 Zeta 分析仪测量了颗粒的流体力学尺寸和表面电荷分析。紫外可见光谱和 Zeta 分析结果表明，AgNPs 已经合成，粒度分布为纳米级，溶液稳定。通过寿命测试和组织病理学分析，研究了合成的 VAC/AgNPs 和 VAC 种子水提取物对蜜蜂的影响。结果表明，在一定剂量下，VAC 种子提取物和 VAC/AgNPs 对蜜蜂无毒，对蜜蜂的寿命有积极影响，并在寿命测试中有助于延长蜜蜂的寿命。此外，在组织病理学检查中也没有发现对肠道健康有不利影响。因此，VAC/AgNPs 被认为是一种很有前景的蜜蜂生物活性剂。

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来源期刊

Veterinary Research Communications 农林科学-兽医学

CiteScore

2.50

自引率

0.00%

发文量

173

审稿时长

3 months

期刊介绍： Veterinary Research Communications publishes fully refereed research articles and topical reviews on all aspects of the veterinary sciences. Interdisciplinary articles are particularly encouraged, as are well argued reviews, even if they are somewhat controversial. The journal is an appropriate medium in which to publish new methods, newly described diseases and new pathological findings, as these are applied to animals. The material should be of international rather than local interest. As it deliberately seeks a wide coverage, Veterinary Research Communications provides its readers with a means of keeping abreast of current developments in the entire field of veterinary science.