Relationships between stenosis severity, functional limitation, pain, and quality of life in patients with cervical spondylotic radiculopathy.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-06-06 eCollection Date: 2024-01-01 DOI:10.55730/1300-0144.5842

Aydın Sinan Apaydin, Musa Güneş

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引用次数: 0

Abstract

Background/aim: This study aimed to examine the relationships between severity of stenosis, pain, functional limitation, disability, and quality of life in patients with cervical spondylotic radiculopathy.

Materials and methods: Patients (45 female, 19 male) with radiculopathy due to spondylotic changes in the cervical spine were included in this study. Stenosis severity (thecal sac cross-sectional area (CSA)), numbness, neck and arm pain severity, functional limitation (Cervical Radiculopathy Impact Scale), disability, and quality of life (EQ-5D-3L General Quality of Life Scale) were evaluated. The study was registered at ClinicalTrials.gov as NCT06001359.

Results: According to CSA values, 28 (43.75%) patients had severe stenosis and 36 (56.25%) had moderate stenosis, and the average CSA was 81.65 ± 10.08 mm². Positive correlations were found between both neck and arm pain and neck disability (r = 0.597, r = 0.359), and negative correlations were found for the General Quality of Life Scale index score and EQ-5D-3L visual analog scale (r = -0.787, r = -0.518). There were significant positive correlations between Cervical Radiculopathy Impact Scale subscales and severity of stenosis, neck and arm pain, numbness, and disability (p < 0.05 for all). A significant negative correlation was observed between Cervical Radiculopathy Impact Scale subscales and quality of life (p < 0.01). Stenosis severity was correlated with pain, neck disability, and quality of life (p < 0.01 for all).

Conclusion: There are direct relationships between cervical spondylotic radiculopathy and neck and arm pain, numbness, disability, and quality of life. Additionally, an increase in the severity of cervical stenosis is associated with an increase in pain and disability.

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颈椎根性病变患者的颈椎狭窄严重程度、功能限制、疼痛和生活质量之间的关系。

背景/目的：本研究旨在探讨颈椎根性病变患者颈椎狭窄严重程度、疼痛、功能受限、残疾和生活质量之间的关系：本研究纳入了因颈椎病变而引起的根性颈椎病患者（45 名女性，19 名男性）。对狭窄严重程度（椎囊横截面积（CSA））、麻木、颈部和手臂疼痛严重程度、功能限制（颈椎病影响量表）、残疾和生活质量（EQ-5D-3L 一般生活质量量表）进行了评估。该研究在 ClinicalTrials.gov 上注册为 NCT06001359：根据 CSA 值，28 例（43.75%）患者为重度狭窄，36 例（56.25%）患者为中度狭窄，平均 CSA 为 81.65 ± 10.08 mm2。颈部和手臂疼痛与颈部残疾之间存在正相关（r = 0.597，r = 0.359），而一般生活质量量表指数评分与 EQ-5D-3L 视觉模拟量表之间存在负相关（r = -0.787，r = -0.518）。颈椎根性病变影响量表分量表与颈椎狭窄严重程度、颈部和手臂疼痛、麻木和残疾之间存在明显的正相关性（均为 p <0.05）。颈椎病影响量表分量表与生活质量之间存在明显的负相关（p < 0.01）。颈椎管狭窄的严重程度与疼痛、颈部残疾和生活质量相关（P < 0.01）：结论：颈椎根性病变与颈部和手臂疼痛、麻木、残疾和生活质量有直接关系。此外，颈椎管狭窄程度的增加与疼痛和残疾的增加有关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.