Trends and gender disparities in the incidence of rheumatic diseases: a regional study from 2018 to 2021.

IF 3.2 3区 医学 Q2 RHEUMATOLOGY
Rheumatology International Pub Date : 2024-12-01 Epub Date: 2024-09-22 DOI:10.1007/s00296-024-05725-y
Gulmira Mutalipova, Dana Bekaryssova, Marlen Yessirkepov, Sholpan Bekarissova
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引用次数: 0

Abstract

Rheumatic diseases encompass a range of entities affecting the musculoskeletal system and connective tissue due to immune dysregulation. These entities include rheumatoid arthritis, systemic lupus erythematosus, and ankylosing spondylitis that present significant medical and social challenges by impacting individuals' quality of life and working capacity. In developing countries, where healthcare access is limited, the burden of these diseases is particularly severe. Analyzing the regional epidemiological characteristics of rheumatic diseases may enhance our understanding of risk factors and aid in developing targeted preventive measures. This study utilized data from the Republican Centre for Health Development in Kazakhstan from 2018 to 2021. The incidence of various rheumatic diseases was examined in the adult population of Shymkent, Kazakhstan, including rheumatoid arthritis, gout, osteoarthritis, systemic lupus erythematosus, dermatomyositis, scleroderma, and ankylosing spondylitis. Shymkent's total number of rheumatic disease cases rose from 52,617 in 2018 to 52,781 in 2021. Primary morbidity increased from 18,381 to 21,677 cases. Incidence rates for systemic lupus erythematosus, systemic scleroderma, and ankylosing spondylitis increased, while cases of rheumatoid arthritis and osteoarthritis showed fluctuation. Gender distribution analysis revealed that women were more frequently affected by rheumatoid arthritis and systemic lupus erythematosus whereas men were more prone to ankylosing spondylitis. The results underscore the need to tailor diagnostic and treatment approaches to account for age-and gender-specific differences in rheumatic diseases. The increased incidence of some diseases calls for new prevention and treatment strategies. This study highlights the significant burden of rheumatic diseases in Shymkent, Kazakhstan and emphasizes the importance of local epidemiological research in adapting medical practices to regional specifics.

风湿病发病率的趋势和性别差异:2018 年至 2021 年的地区研究。
风湿病包括一系列因免疫失调而影响肌肉骨骼系统和结缔组织的疾病。这些疾病包括类风湿性关节炎、系统性红斑狼疮和强直性脊柱炎,它们影响着个人的生活质量和工作能力,给医疗和社会带来了巨大挑战。在医疗条件有限的发展中国家,这些疾病造成的负担尤为沉重。分析风湿病的地区流行病学特征,可以加深我们对风险因素的了解,有助于制定有针对性的预防措施。本研究利用了哈萨克斯坦共和国卫生发展中心 2018 年至 2021 年的数据。研究了哈萨克斯坦什姆肯特市成年人口中各种风湿性疾病的发病率,包括类风湿性关节炎、痛风、骨关节炎、系统性红斑狼疮、皮肌炎、硬皮病和强直性脊柱炎。什姆肯特的风湿病病例总数从 2018 年的 52 617 例增加到 2021 年的 52 781 例。原发病从18381例增加到21677例。系统性红斑狼疮、系统性硬皮病和强直性脊柱炎的发病率有所上升,而类风湿性关节炎和骨关节炎的病例则出现波动。性别分布分析表明,类风湿性关节炎和系统性红斑狼疮多发于女性,而强直性脊柱炎多发于男性。研究结果表明,有必要根据风湿病的年龄和性别差异,调整诊断和治疗方法。一些疾病发病率的增加要求我们采取新的预防和治疗策略。这项研究凸显了哈萨克斯坦西姆肯特市风湿病的沉重负担,并强调了当地流行病学研究在使医疗实践适应地区具体情况方面的重要性。
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来源期刊
Rheumatology International
Rheumatology International 医学-风湿病学
CiteScore
7.30
自引率
5.00%
发文量
191
审稿时长
16. months
期刊介绍: RHEUMATOLOGY INTERNATIONAL is an independent journal reflecting world-wide progress in the research, diagnosis and treatment of the various rheumatic diseases. It is designed to serve researchers and clinicians in the field of rheumatology. RHEUMATOLOGY INTERNATIONAL will cover all modern trends in clinical research as well as in the management of rheumatic diseases. Special emphasis will be given to public health issues related to rheumatic diseases, applying rheumatology research to clinical practice, epidemiology of rheumatic diseases, diagnostic tests for rheumatic diseases, patient reported outcomes (PROs) in rheumatology and evidence on education of rheumatology. Contributions to these topics will appear in the form of original publications, short communications, editorials, and reviews. "Letters to the editor" will be welcome as an enhancement to discussion. Basic science research, including in vitro or animal studies, is discouraged to submit, as we will only review studies on humans with an epidemological or clinical perspective. Case reports without a proper review of the literatura (Case-based Reviews) will not be published. Every effort will be made to ensure speed of publication while maintaining a high standard of contents and production. Manuscripts submitted for publication must contain a statement to the effect that all human studies have been reviewed by the appropriate ethics committee and have therefore been performed in accordance with the ethical standards laid down in an appropriate version of the 1964 Declaration of Helsinki. It should also be stated clearly in the text that all persons gave their informed consent prior to their inclusion in the study. Details that might disclose the identity of the subjects under study should be omitted.
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