Changes in walking speed following resistance training in people with multiple sclerosis: A systematic review and meta-analysis.

IF 2.2 4区医学 Q1 REHABILITATION

PM&R Pub Date : 2024-09-23 DOI:10.1002/pmrj.13255

Connor McManaman, Brianna Novak, Lorna Paul, Scott Rooney

{"title":"Changes in walking speed following resistance training in people with multiple sclerosis: A systematic review and meta-analysis.","authors":"Connor McManaman, Brianna Novak, Lorna Paul, Scott Rooney","doi":"10.1002/pmrj.13255","DOIUrl":null,"url":null,"abstract":"Background: Reduced walking ability, especially decreased gait speed, is one of the most common and disabling impairments reported by people with multiple sclerosis (MS). Considering the impact of muscle strength on walking ability, resistance training may have the potential to improve walking speed in MS. Therefore, this systematic review and meta-analysis aims to evaluate the effect of lower limb resistance training on walking speed in people with MS.Methods: Seven databases (CINAHL, MEDLINE, The Allied and Complimentary Medicine Database, Web of Science, Physiotherapy Evidence Database [PEDro], PsycINFO, and Sports Medicine and Education Index) were searched in March 2024 for studies that met the following eligibility criteria: randomized controlled trials investigating the effects of resistance training interventions on objective measures of walking speed in people with MS. Risk of bias was assessed using the PEDro scale. Meta-analysis was performed to quantify intervention effect using a random effects model.Results: Twelve randomized controlled trials were included, reporting data on 425 individuals with MS. Participants had mostly relapsing-remitting MS (85%) and a mild-moderate level of disability (Expanded Disability Status Score 1.0-6.0). Results of the meta-analysis (based on 7 of the included studies) indicated a significant yet variable improvement in walking speed in favor of the intervention (0.10 m/s, 95% confidence interval 0.01-0.19, p < .05). Sensitivity analysis indicates that larger improvements in walking speed were found over tests covering shorter distances.Conclusions: Resistance training was found to significantly improve walking speed in people with MS. However, variability in results were noted across studies; accordingly, future research should determine how variables-particularly related to resistance training prescription-influence the intervention effect.","PeriodicalId":20354,"journal":{"name":"PM&R","volume":" ","pages":""},"PeriodicalIF":2.2000,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"PM&R","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1002/pmrj.13255","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"REHABILITATION","Score":null,"Total":0}

引用次数: 0

Abstract

Background: Reduced walking ability, especially decreased gait speed, is one of the most common and disabling impairments reported by people with multiple sclerosis (MS). Considering the impact of muscle strength on walking ability, resistance training may have the potential to improve walking speed in MS. Therefore, this systematic review and meta-analysis aims to evaluate the effect of lower limb resistance training on walking speed in people with MS.

Methods: Seven databases (CINAHL, MEDLINE, The Allied and Complimentary Medicine Database, Web of Science, Physiotherapy Evidence Database [PEDro], PsycINFO, and Sports Medicine and Education Index) were searched in March 2024 for studies that met the following eligibility criteria: randomized controlled trials investigating the effects of resistance training interventions on objective measures of walking speed in people with MS. Risk of bias was assessed using the PEDro scale. Meta-analysis was performed to quantify intervention effect using a random effects model.

Results: Twelve randomized controlled trials were included, reporting data on 425 individuals with MS. Participants had mostly relapsing-remitting MS (85%) and a mild-moderate level of disability (Expanded Disability Status Score 1.0-6.0). Results of the meta-analysis (based on 7 of the included studies) indicated a significant yet variable improvement in walking speed in favor of the intervention (0.10 m/s, 95% confidence interval 0.01-0.19, p < .05). Sensitivity analysis indicates that larger improvements in walking speed were found over tests covering shorter distances.

Conclusions: Resistance training was found to significantly improve walking speed in people with MS. However, variability in results were noted across studies; accordingly, future research should determine how variables-particularly related to resistance training prescription-influence the intervention effect.

查看原文本刊更多论文

多发性硬化症患者进行阻力训练后步行速度的变化：系统回顾和荟萃分析。

背景：行走能力下降，尤其是步速下降，是多发性硬化症（MS）患者最常见的致残障碍之一。考虑到肌肉力量对行走能力的影响，阻力训练可能具有提高多发性硬化症患者行走速度的潜力。因此，本系统综述和荟萃分析旨在评估下肢阻力训练对多发性硬化症患者行走速度的影响：于 2024 年 3 月在七个数据库（CINAHL、MEDLINE、联合与辅助医学数据库、Web of Science、物理治疗证据数据库 [PEDro]、PsycINFO 和运动医学与教育索引）中检索了符合以下资格标准的研究：调查阻力训练干预对多发性硬化症患者步行速度客观测量的影响的随机对照试验。偏倚风险采用 PEDro 量表进行评估。采用随机效应模型进行元分析以量化干预效果：共纳入了 12 项随机对照试验，报告了 425 名多发性硬化症患者的数据。参与者大多为复发缓解型多发性硬化症患者（85%），残疾程度为轻度-中度（残疾状况扩展评分 1.0-6.0）。荟萃分析（基于纳入的 7 项研究）结果表明，干预对步行速度有显著改善，但改善程度不一（0.10 米/秒，95% 置信区间为 0.01-0.19，P 结论）：研究发现，阻力训练可显著提高多发性硬化症患者的步行速度。然而，不同研究的结果存在差异；因此，未来的研究应确定变量（尤其是与阻力训练处方相关的变量）如何影响干预效果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

PM&R REHABILITATION-SPORT SCIENCES

CiteScore

4.30

自引率

4.80%

发文量

187

审稿时长

4-8 weeks

期刊介绍： Topics covered include acute and chronic musculoskeletal disorders and pain, neurologic conditions involving the central and peripheral nervous systems, rehabilitation of impairments associated with disabilities in adults and children, and neurophysiology and electrodiagnosis. PM&R emphasizes principles of injury, function, and rehabilitation, and is designed to be relevant to practitioners and researchers in a variety of medical and surgical specialties and rehabilitation disciplines including allied health.