Unveiling Disparities: Analyzing Hispanic Inclusion in Liver Cancer Research Databases in the United States.

IF 3.2 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Gabriela Arroyo Figueroa, Tim F Greten, Cecilia Monge Bonilla
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引用次数: 0

Abstract

Primary liver cancer, including hepatocellular carcinoma and intrahepatic cholangiocarcinoma was the sixth leading cause of cancer death in the United States in 2023. Hispanic people constitute approximately 19% of the nation's total population according to the US Census. Hispanic patients have the highest relative incidence rates of liver cancer compared to non-Hispanic Whites and non-Hispanic Blacks, a disparity frequently overlooked in cancer research. In this study, our primary objective was to analyze the potential underrepresentation of Hispanic individuals in liver cancer research databases. We identified databases that had liver cancer-specific studies and be population-based in the United States. Our search yielded 7 cancer genomic databases, which were analyzed according to incidence percentages across ethnicity and race categories. Our study included 3104 patients; ethnic data was not reported for 13.1% (n = 406) of the patients. Samples were predominantly from individuals who identified as Not Hispanic (81.0%), Hispanic individuals represented 5.9%. Race was reported as follows: non-Hispanic Whites (61.0%), Asians (22.0%), non-Hispanic Blacks (5.4%), Other (3.1%), Native American/American Indian/Alaska Native (0.4%), Pacific Islander/Native Hawaiian (0.2%) and not reported (7.9%). These findings collectively underscore significant disparities in the representation of ethnic and racial groups, particularly Hispanics. Given the present racial and ethnic demographics of the US population and the projected surge in the Hispanic population in forthcoming years, it becomes imperative to address health disparities that may worsen without efforts to enhance proper inclusion in cancer research.

揭示差距:分析美国肝癌研究数据库中的西班牙裔纳入情况。
原发性肝癌(包括肝细胞癌和肝内胆管癌)是 2023 年美国第六大癌症死因。根据美国人口普查,西班牙裔人口约占全美总人口的 19%。与非西班牙裔白人和非西班牙裔黑人相比,西班牙裔患者的肝癌相对发病率最高,这是癌症研究中经常被忽视的一个差异。在这项研究中,我们的主要目标是分析肝癌研究数据库中拉美裔个体的代表性可能不足的情况。我们确定了有肝癌特定研究且以美国人口为基础的数据库。我们搜索到了 7 个癌症基因组数据库,并根据不同种族和人种的发病率进行了分析。我们的研究纳入了 3104 名患者,其中 13.1%(n = 406)的患者未报告种族数据。样本主要来自非西班牙裔患者(81.0%),西班牙裔患者占 5.9%。种族报告如下:非西班牙裔白人(61.0%)、亚裔(22.0%)、非西班牙裔黑人(5.4%)、其他(3.1%)、美洲原住民/美洲印第安人/阿拉斯加原住民(0.4%)、太平洋岛民/夏威夷原住民(0.2%)和未报告(7.9%)。这些调查结果表明,各民族和种族群体,特别是西班牙裔群体的代表性存在显著差异。鉴于目前美国人口的种族和民族人口构成,以及预计未来几年西班牙裔人口的激增,如果不努力加强癌症研究中的适当包容,健康差距可能会恶化,因此解决这一问题势在必行。
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来源期刊
Journal of Racial and Ethnic Health Disparities
Journal of Racial and Ethnic Health Disparities PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
CiteScore
7.30
自引率
5.10%
发文量
263
期刊介绍: Journal of Racial and Ethnic Health Disparities reports on the scholarly progress of work to understand, address, and ultimately eliminate health disparities based on race and ethnicity. Efforts to explore underlying causes of health disparities and to describe interventions that have been undertaken to address racial and ethnic health disparities are featured. Promising studies that are ongoing or studies that have longer term data are welcome, as are studies that serve as lessons for best practices in eliminating health disparities. Original research, systematic reviews, and commentaries presenting the state-of-the-art thinking on problems centered on health disparities will be considered for publication. We particularly encourage review articles that generate innovative and testable ideas, and constructive discussions and/or critiques of health disparities.Because the Journal of Racial and Ethnic Health Disparities receives a large number of submissions, about 30% of submissions to the Journal are sent out for full peer review.
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