Ureteral access sheaths in RIRS: a retrospective, comparative, single-center study.

Q3 Pharmacology, Toxicology and Pharmaceutics

Journal of Basic and Clinical Physiology and Pharmacology Pub Date : 2024-09-20 DOI:10.1515/jbcpp-2024-0142

Giuseppe Celentano, Biagio Barone, Roberto La Rocca, Matteo Massanova, Luigi Napolitano, Domenico Prezioso, Marco Abate, Benito Fabio Mirto, Ferdinando Fusco, Felice Crocetto

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引用次数: 0

Abstract

Objectives: To evaluate the use of ureteral access sheaths (UAS) in reducing operative time and complications, as well as improving stone-free rates (SFR), while assessing their overall safety and efficiency.

Methods: Data regarding 234 patients who underwent retrograde intrarenal surgery (RIRS) for stones up to 3 cm between January 2017 and March 2020 were retrospectively analyzed. About 52.5 % of procedures were performed utilizing a UAS. Differences in operative time, fluoroscopy time, stone-free rate, and complications were analyzed between procedures with and without UAS and stratified, according to stone burden size, into three groups (Group A: 0.5-1 cm; Group B: 1-2 cm; Group C: 2-3 cm).

Results: Operative time, fluoroscopy time, and residual fragments size were lower in RIRS without UAS, respectively, 54.27 ± 24.02 vs. 62.23 ± 22.66 min (p=0.010), 2.72 ± 0.89 vs. 4.44 ± 1.67 min (p<0.0001), and 3.85 ± 0.813 vs. 4.60 ± 0.83 mm (p=0.011). Considering stone burden, operative time was lower in RIRS without UAS for Group A (36.40 ± 8.555 vs. 46.05 ± 6.332 min) (p<0.0001) while higher for Group B (60.39 ± 18.785 vs. 50.14 ± 5.812 min) (p=0.002). Similarly, fluoroscopy time was lower in RIRS without UAS in every group, respectively, 2.11 ± 0.34 vs. 2.74 ± 0.57 min (p<0.0001), 2.94 ± 0.51 vs. 4.72 ± 0.37 min (p<0.0001), and 3.78 ± 1.26 vs. 6.79 ± 1.17 min (p<0.0001). Only Group C had a statistically significant difference in residual fragment size without UAS (3.89 ± 0.782 vs. 4.75 ± 0.886 mm) (p=0.050).

Conclusions: UAS should be carefully evaluated considering the increased fluoroscopy time and the differences in operative time related to different stone burdens.

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RIRS 中的输尿管通路鞘：一项回顾性、比较性、单中心研究。

目的：评估输尿管通道鞘（UAS）在缩短手术时间、减少并发症、提高无结石率（SFR）方面的作用，同时评估其整体安全性和效率：评估输尿管通道鞘（UAS）在缩短手术时间、减少并发症、提高无结石率（SFR）方面的应用，同时评估其整体安全性和效率：回顾性分析了2017年1月至2020年3月期间234名接受逆行肾内手术（RIRS）治疗3厘米以下结石患者的数据。约52.5%的手术是利用无人机系统进行的。分析了使用和未使用UAS的手术在手术时间、透视时间、无石率和并发症方面的差异，并根据结石大小分为三组（A组：0.5-1厘米；B组：1-2厘米；C组：2-3厘米）：结果：不使用 UAS 的 RIRS 的手术时间、透视时间和残留碎片大小分别为：54.27 ± 24.02 分钟 vs 62.23 ± 22.66 分钟（P=0.010）、2.72 ± 0.89 分钟 vs 4.44 ± 1.67 分钟（P结论：考虑到结石的大小，应谨慎评估 UAS：考虑到透视时间的增加以及与不同结石负荷相关的手术时间差异，应仔细评估 UAS。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Basic and Clinical Physiology and Pharmacology Pharmacology, Toxicology and Pharmaceutics-Pharmacology

CiteScore

3.90

自引率

0.00%

发文量

期刊介绍： The Journal of Basic and Clinical Physiology and Pharmacology (JBCPP) is a peer-reviewed bi-monthly published journal in experimental medicine. JBCPP publishes novel research in the physiological and pharmacological sciences, including brain research; cardiovascular-pulmonary interactions; exercise; thermal control; haematology; immune response; inflammation; metabolism; oxidative stress; and phytotherapy. As the borders between physiology, pharmacology and biochemistry become increasingly blurred, we also welcome papers using cutting-edge techniques in cellular and/or molecular biology to link descriptive or behavioral studies with cellular and molecular mechanisms underlying the integrative processes. Topics: Behavior and Neuroprotection, Reproduction, Genotoxicity and Cytotoxicity, Vascular Conditions, Cardiovascular Function, Cardiovascular-Pulmonary Interactions, Oxidative Stress, Metabolism, Immune Response, Hematological Profile, Inflammation, Infection, Phytotherapy.