Clinico-demographic profile and visual outcomes of pseudophakic bullous keratopathy in a multi-tier eyecare network in India.

IF 2.1 4区 医学 Q2 OPHTHALMOLOGY
Indian Journal of Ophthalmology Pub Date : 2025-03-01 Epub Date: 2024-09-19 DOI:10.4103/IJO.IJO_323_24
Anthony Vipin Das, Soujanya Kaup, Sujata Das
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引用次数: 0

Abstract

Purpose: The purpose of this study is to present the clinico-demographic characteristics of pseudophakic bullous keratopathy (PBK), its visual outcomes, factors associated with the choice of treatment, and poor visual outcomes of PBK.

Methods: In this hospital-based retrospective study, electronic medical records data of new patients who presented to a multi-tier ophthalmology hospital network in India (November 2010-June 2022) were extracted. Patients with at least 4 weeks of follow-up were analyzed for visual outcome data. Bivariate analysis and multivariate logistic regression were used to determine the factors associated with the treatment choice and poor visual outcomes.

Results: Of the 3,323,247 electronic records (with an average follow-up of 293 days) examined, 10,522 eyes of 10,158 patients (0.3%) had PBK. The majority were managed non-surgically ( n = 7372; 70.1%), with increased odds of poor visual outcome by 3.46 times (AdjOR: 3.04-3.92, P < 0.001). Those belonging to the non-paying category had higher odds of poor visual outcome (AdjOR: 1.48, 95%CI: 1.29-1.69; P < 0.001). Surgical management improved vision by 0.72 logMAR (95%CI: 0.60-0.73; P < 0.001). A total of 41.2% ( n = 113/274) of cases that underwent Descemet's membrane endothelial keratoplasty and 18.4% ( n = 285/1551) of Descemet's stripping endothelial keratoplasty attained last follow-up visual acuity (LVA) of 6/18 or better.

Conclusion: About three in every thousand patients had PBK. Surgical interventions improved visual acuity significantly. About four in ten patients who underwent DMEK attained a vision of 6/18 or better at the last follow-up visit. Markers of lower socioeconomic strata were independently associated with poor visual outcomes.

印度多层次眼科网络中假性角膜牛皮状角膜病的临床人口学特征和视觉效果。
目的:本研究旨在介绍假性角膜牛皮样角膜病(PBK)的临床-人口学特征、视觉疗效、与治疗选择相关的因素以及 PBK 的不良视觉疗效:在这项以医院为基础的回顾性研究中,研究人员提取了在印度一家多级眼科医院网络就诊的新患者的电子病历数据(2010 年 11 月至 2022 年 6 月)。对随访至少 4 周的患者进行了视觉结果数据分析。采用双变量分析和多变量逻辑回归确定与治疗选择和不良视觉结果相关的因素:在3,323,247份电子病历(平均随访293天)中,10,158名患者中有10,522只眼睛(0.3%)患有PBK。大多数患者接受了非手术治疗(n = 7372;70.1%),视力不良的几率增加了 3.46 倍(AdjOR:3.04-3.92,P < 0.001)。非付费患者视力不良的几率更高(AdjOR:1.48,95%CI:1.29-1.69;P < 0.001)。手术治疗使视力提高了 0.72 logMAR (95%CI: 0.60-0.73; P < 0.001)。41.2%(n = 113/274)的戴斯迈膜内皮角膜移植术病例和18.4%(n = 285/1551)的戴斯迈剥离内皮角膜移植术病例的最后随访视力(LVA)达到6/18或更佳:结论:每千名患者中约有三人接受了去角膜剥脱内皮角膜移植术。结论:每千名患者中约有三人患有 PBK,手术治疗可明显改善视力。接受 DMEK 的患者中,约有十分之四的人在最后一次随访时视力达到 6/18 或更佳。较低社会经济阶层的标志与较差的视力结果独立相关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
3.80
自引率
19.40%
发文量
1963
审稿时长
38 weeks
期刊介绍: Indian Journal of Ophthalmology covers clinical, experimental, basic science research and translational research studies related to medical, ethical and social issues in field of ophthalmology and vision science. Articles with clinical interest and implications will be given preference.
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