Smoking is a predominant risk factor for coronary artery disease among Indians.

IF 1.9
Bioinformation Pub Date : 2024-07-31 eCollection Date: 2024-01-01 DOI:10.6026/973206300200719
Rafae Taqiuddin, Mohammed Jaffer Ali, Aishwarya Kimmatkar, Nimerta Lohana, Anveshak, Maarya Mohammed Siddiqui, Yasir Adil El Rashid Mohamed, Mohamed Elfatih Musaab Ibrahim Mohamed, Rida Minhaj, Mohammed Abdul Mateen
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Abstract

Smoking has emerged as a predominant risk factor for coronary artery disease (CAD) in India, contributing significantly to the country's rising cardiovascular morbidity and mortality rates. The adverse effects of tobacco on cardiovascular health are well-documented, exacerbating a public health challenge in a nation with a high prevalence of smoking. Therefore, it is of interest to analyse the impact of smoking on the incidence and progression of coronary artery disease among the Indian population, emphasizing the need for targeted public health interventions to mitigate this risk factor. We included 1000 adults were enrolled from January to July 2023. The group comprised 500 CAD patients (cases) and 500 individuals without CAD (controls). We gathered information on demographics, smoking habits & other CAD risk factors. To assess the relationships between smoking, CAD, and other variables, we utilized multivariate logistic regression. The analysis revealed that current smokers had a substantially increased likelihood of CAD, with an unadjusted odds ratio (OR) of 3.20 (95% CI: 2.45-4.18), compared to non-smokers. This association remained significant even after adjusting for confounders, with an adjusted OR of 2.80 (95% CI: 2.10-3.75). The study confirms smoking as a critical, Adaptable risk element for CAD, independently increasing the risk of the disease. Smoking significantly elevates the risk of developing coronary artery disease among Indians. Comprehensive anti-smoking campaigns and stringent tobacco control policies are imperative to reduce the burden of CAD. Public health strategies must focus on awareness, prevention, and cessation support to combat this major health threat effectively.

吸烟是印度人患冠心病的主要风险因素。
在印度,吸烟已成为冠状动脉疾病(CAD)的主要危险因素,这也是印度心血管疾病发病率和死亡率不断上升的重要原因。烟草对心血管健康的不利影响已得到充分证实,这在一个吸烟率很高的国家加剧了公共卫生挑战。因此,我们有兴趣分析吸烟对印度人冠心病发病率和病情发展的影响,强调有必要采取有针对性的公共卫生干预措施来降低这一风险因素。我们在 2023 年 1 月至 7 月期间招募了 1000 名成年人。其中包括 500 名 CAD 患者(病例)和 500 名无 CAD 患者(对照组)。我们收集了有关人口统计学、吸烟习惯和其他心血管疾病风险因素的信息。为了评估吸烟、冠状动脉粥样硬化和其他变量之间的关系,我们采用了多变量逻辑回归法。分析结果显示,与非吸烟者相比,当前吸烟者患 CAD 的可能性大大增加,未经调整的几率比(OR)为 3.20(95% CI:2.45-4.18)。即使在对混杂因素进行调整后,这种关联仍然很明显,调整后的 OR 为 2.80(95% CI:2.10-3.75)。这项研究证实,吸烟是诱发冠状动脉粥样硬化症的一个关键、可调整的风险因素,会独立增加该疾病的风险。吸烟会大大增加印度人罹患冠状动脉疾病的风险。全面的禁烟运动和严格的烟草控制政策对于减轻冠状动脉粥样硬化的负担至关重要。公共卫生战略必须侧重于宣传、预防和戒烟支持,以有效对抗这一重大健康威胁。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Bioinformation
Bioinformation MATHEMATICAL & COMPUTATIONAL BIOLOGY-
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