Hepatic Adenomatosis in a Transgender Man on Gender-Affirming Testosterone Therapy.

IF 0.6 Q4 GASTROENTEROLOGY & HEPATOLOGY
ACG Case Reports Journal Pub Date : 2024-09-11 eCollection Date: 2024-09-01 DOI:10.14309/crj.0000000000001483
Yuting Huang, Nicole M Loo, Alice Y Chang, Zachary Yu, Amanda L McKenna, Charles Ritchie, Allie M Metcalfe, Raouf E Nakhleh, Murli Krishna, C Burcin Taner, Liu Yang
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引用次数: 0

Abstract

The management of hepatic adenoma in transgender individuals undergoing gender-affirming hormone therapy remains unclear, especially whether treatment should be based on sex assigned at birth or therapy patient received. We presented a transgender man, female at birth, with hepatic adenomatosis with molecular profile differed from typical adenomas in cisgender males on testosterone. Discontinuing testosterone led to autoinfarction of the adenoma, allowing the avoidance of invasive treatments and resumption of gender-affirming hormone therapy. This case underscores the necessity for personalized care in the growing transgender population and challenges current consensus of treatment based on sex assigned at birth, emphasizing a tailored approach.

一名接受性别确认睾酮疗法的变性人的肝腺瘤病。
接受性别确认激素治疗的变性人的肝腺瘤治疗方法仍不明确,尤其是治疗是否应基于出生时的性别分配或患者接受的治疗。我们介绍了一名出生时为女性的变性男性,他患有肝腺瘤,其分子特征与使用睾酮的顺性别男性的典型腺瘤不同。停用睾酮导致腺瘤自体梗死,从而避免了侵入性治疗,恢复了性别确认激素疗法。该病例强调了为日益增多的变性人提供个性化治疗的必要性,并挑战了目前根据出生时的性别进行治疗的共识,强调了量身定制的方法。
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来源期刊
ACG Case Reports Journal
ACG Case Reports Journal GASTROENTEROLOGY & HEPATOLOGY-
自引率
14.30%
发文量
170
审稿时长
12 weeks
期刊介绍: ACG Case Reports Journal is a peer-reviewed, open-access publication that provides GI and hepatology fellows, private practice clinicians, and other healthcare providers an opportunity to share interesting case reports with their peers and with leaders in the field. ACG Case Reports Journal publishes case reports, images, videos and letters to the editor in all topics of gastroenterology and hepatology, including: Biliary Colon Endoscopy Esophagus Functional Bowel Disorders Inflammatory Bowel Disease Liver Nutrition and Obesity Pancreas Pathology Pediatric Small Bowel Stomach.
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