A preliminary study of renal function for renal artery stenosis using multiparametric magnetic resonance imaging.

IF 2.3 3区医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Abdominal Radiology Pub Date : 2024-09-20 DOI:10.1007/s00261-024-04586-0

Long Zhao, Xin-Yu Tong, Zi-Han Ning, Guo-Qin Wang, Feng-Bo Xu, Jia-Yi Liu, Shuang Li, Nan Zhang, Zhong-Hua Sun, Xi-Hai Zhao, Lei Xu

{"title":"A preliminary study of renal function for renal artery stenosis using multiparametric magnetic resonance imaging.","authors":"Long Zhao, Xin-Yu Tong, Zi-Han Ning, Guo-Qin Wang, Feng-Bo Xu, Jia-Yi Liu, Shuang Li, Nan Zhang, Zhong-Hua Sun, Xi-Hai Zhao, Lei Xu","doi":"10.1007/s00261-024-04586-0","DOIUrl":null,"url":null,"abstract":"Objective: To comprehensively evaluate the renal structure and function of patients with renal artery stenosis (RAS) using multiparametric magnetic resonance imaging (MRI), and analyze the correlation between magnetic resonance (MR) parameters and renal function.Materials and methods: Renal multiparametric MRI was conducted on 62 patients with RAS utilizing a Philips Ingenia CX 3.0 T MRI system. The scanning protocols encompassed arterial spin labeling, phase contrast MRI, diffusion weighted imaging, T1 mapping, and blood oxygen level-dependent MRI. All patients underwent radionuclide renal dynamic imaging to calculate the glomerular filtration rate (GFR) for assessing renal function.Results: Most MR parameters were correlated with GFR: renal parenchymal volume (R = 0.603), whole kidney renal blood flow (RBF) (R = 0.192), renal cortical RBF (R = 0.294), renal artery mean velocity (R = 0.593), stroke volume (R = 0.599), mean flux (R = 0.629), renal cortical apparent diffusion coefficient (ADC) (R = 0.466), medullary ADC (R = 0.332), cortical T1 value (R = - 0.206), corticomedullary T1 difference (R = 0.204), cortical T2* value (R = 0.448), and medullary T2* value (R = 0.272). The best prediction model for GFR using multiparametric MRI was obtained, including renal PV, whole kidney RBF, cortical RBF, mean velocity, mean flux, and CMD T1.Conclusion: Multiparametric MRI is a novel noninvasive examination method that can effectively and comprehensively assess the renal structure and function of RAS.","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":null,"pages":null},"PeriodicalIF":2.3000,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Abdominal Radiology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s00261-024-04586-0","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}

引用次数: 0

Abstract

Objective: To comprehensively evaluate the renal structure and function of patients with renal artery stenosis (RAS) using multiparametric magnetic resonance imaging (MRI), and analyze the correlation between magnetic resonance (MR) parameters and renal function.

Materials and methods: Renal multiparametric MRI was conducted on 62 patients with RAS utilizing a Philips Ingenia CX 3.0 T MRI system. The scanning protocols encompassed arterial spin labeling, phase contrast MRI, diffusion weighted imaging, T1 mapping, and blood oxygen level-dependent MRI. All patients underwent radionuclide renal dynamic imaging to calculate the glomerular filtration rate (GFR) for assessing renal function.

Results: Most MR parameters were correlated with GFR: renal parenchymal volume (R = 0.603), whole kidney renal blood flow (RBF) (R = 0.192), renal cortical RBF (R = 0.294), renal artery mean velocity (R = 0.593), stroke volume (R = 0.599), mean flux (R = 0.629), renal cortical apparent diffusion coefficient (ADC) (R = 0.466), medullary ADC (R = 0.332), cortical T1 value (R = - 0.206), corticomedullary T1 difference (R = 0.204), cortical T2^* value (R = 0.448), and medullary T2^* value (R = 0.272). The best prediction model for GFR using multiparametric MRI was obtained, including renal PV, whole kidney RBF, cortical RBF, mean velocity, mean flux, and CMD T1.

Conclusion: Multiparametric MRI is a novel noninvasive examination method that can effectively and comprehensively assess the renal structure and function of RAS.

查看原文本刊更多论文

利用多参数磁共振成像对肾动脉狭窄的肾功能进行初步研究。

目的利用多参数磁共振成像（MRI）全面评估肾动脉狭窄（RAS）患者的肾脏结构和功能，并分析磁共振（MR）参数与肾功能之间的相关性：利用飞利浦 Ingenia CX 3.0 T MRI 系统对 62 名 RAS 患者进行了肾脏多参数 MRI 扫描。扫描方案包括动脉自旋标记、相位对比 MRI、弥散加权成像、T1 图谱和血氧水平依赖性 MRI。所有患者都接受了放射性核素肾动态成像，以计算肾小球滤过率（GFR）来评估肾功能：大多数 MR 参数与 GFR 相关：肾实质体积（R = 0.603）、全肾肾血流量 (RBF) （R = 0.192）、肾皮质 RBF（R = 0.294）、肾动脉平均速度（R = 0.593）、搏出量（R = 0.599）、平均通量（R = 0.629）、肾皮质表观弥散系数（ADC）（R = 0.466）、髓质 ADC（R = 0.332）、皮质 T1 值（R = - 0.206）、皮质髓质 T1 差（R = 0.204）、皮质 T2* 值（R = 0.448）和髓质 T2* 值（R = 0.272）。利用多参数 MRI 获得的 GFR 最佳预测模型包括肾 PV、全肾 RBF、皮质 RBF、平均速度、平均通量和 CMD T1：结论：多参数磁共振成像是一种新型的无创检查方法，能有效、全面地评估 RAS 的肾脏结构和功能。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Abdominal Radiology Medicine-Radiology, Nuclear Medicine and Imaging

CiteScore

5.20

自引率

8.30%

发文量

334

期刊介绍： Abdominal Radiology seeks to meet the professional needs of the abdominal radiologist by publishing clinically pertinent original, review and practice related articles on the gastrointestinal and genitourinary tracts and abdominal interventional and radiologic procedures. Case reports are generally not accepted unless they are the first report of a new disease or condition, or part of a special solicited section. Reasons to Publish Your Article in Abdominal Radiology: · Official journal of the Society of Abdominal Radiology (SAR) · Published in Cooperation with: European Society of Gastrointestinal and Abdominal Radiology (ESGAR) European Society of Urogenital Radiology (ESUR) Asian Society of Abdominal Radiology (ASAR) · Efficient handling and Expeditious review · Author feedback is provided in a mentoring style · Global readership · Readers can earn CME credits