Practical electrochemical hydrogenation of nitriles at the nickel foam cathode.

IF 9.3 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Green Chemistry Pub Date : 2024-09-05 DOI:10.1039/d4gc03446e

Rok Narobe, Marcel Nicolas Perner, María de Jesús Gálvez-Vázquez, Conrad Kuhwald, Martin Klein, Peter Broekmann, Sina Rösler, Bertram Cezanne, Siegfried R Waldvogel

引用次数: 0

Abstract

We report a scalable hydrogenation method for nitriles based on cost-effective materials in a very simple two-electrode setup under galvanostatic conditions. All components are commercially and readily available. The method is very easy to conduct and applicable to a variety of nitrile substrates, leading exclusively to primary amine products in yields of up to 89% using an easy work-up protocol. Importantly, this method is readily transferable from the milligram scale in batch-type screening cells to the multi-gram scale in a flow-type electrolyser. The transfer to flow electrolysis enabled us to achieve a notable 20 g day^-1 productivity of phenylethylamine at a geometric current density of 50 mA cm^-2 in a flow-type electrolyser with 48 cm² electrodes. It is noteworthy that this method is sustainable in terms of process safety and reusability of components.

查看原文本刊更多论文

在泡沫镍阴极上对腈进行实际电化学氢化。

我们报告了一种可扩展的腈类氢化方法，该方法基于极具成本效益的材料，采用非常简单的双电极装置，在电静电条件下进行。所有元件均可从市场上买到。该方法非常容易操作，适用于各种腈基质，通过简单的操作步骤就能得到伯胺产品，产率高达 89%。重要的是，这种方法可以很容易地从批量式筛选池中的毫克级转移到流动式电解槽中的多克级。通过向流动电解的转移，我们得以在一个拥有 48 平方厘米电极的流动型电解槽中，以 50 mA cm-2 的几何电流密度实现了 20 克/天-1 的苯乙胺生产率。值得注意的是，这种方法在工艺安全和部件可重复使用方面具有可持续性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Green Chemistry 化学-化学综合

CiteScore

16.10

自引率

7.10%

发文量

677

审稿时长

1.4 months

期刊介绍： Green Chemistry is a journal that provides a unique forum for the publication of innovative research on the development of alternative green and sustainable technologies. The scope of Green Chemistry is based on the definition proposed by Anastas and Warner (Green Chemistry: Theory and Practice, P T Anastas and J C Warner, Oxford University Press, Oxford, 1998), which defines green chemistry as the utilisation of a set of principles that reduces or eliminates the use or generation of hazardous substances in the design, manufacture and application of chemical products. Green Chemistry aims to reduce the environmental impact of the chemical enterprise by developing a technology base that is inherently non-toxic to living things and the environment. The journal welcomes submissions on all aspects of research relating to this endeavor and publishes original and significant cutting-edge research that is likely to be of wide general appeal. For a work to be published, it must present a significant advance in green chemistry, including a comparison with existing methods and a demonstration of advantages over those methods.