Determinant of 30-day Mortality of Pulmonary Legionellosis: Do Co-Infections Matter?

IF 3.8 4区医学 Q2 IMMUNOLOGY

Open Forum Infectious Diseases Pub Date : 2024-09-13 DOI:10.1093/ofid/ofae529

Takahiro Matsuo, Sebastian Wurster, Ying Jiang, Jeffrey Tarrand, Scott E Evans, Dimitrios P Kontoyiannis

引用次数: 0

Abstract

We retrospectively reviewed 64 cancer patients with pulmonary legionellosis (Legionella pneumophila in 73%). Nearly all patients received Legionella-active antibiotics, yet 30-day mortality was 23%. Independent predictors of 30-day mortality were hyponatremia, bilateral lung involvement, and SOFA score ≥5. Lung co-infections were common (31%) but did not significantly increase mortality.

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肺军团菌病 30 天死亡率的决定因素：合并感染重要吗？

我们对 64 名患肺军团菌病的癌症患者（73% 患有嗜肺军团菌病）进行了回顾性研究。几乎所有患者都接受了军团菌活性抗生素治疗，但 30 天死亡率为 23%。低钠血症、双肺受累和 SOFA 评分≥5 分是预测 30 天死亡率的独立因素。肺部合并感染很常见（31%），但并不会显著增加死亡率。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Open Forum Infectious Diseases Medicine-Neurology (clinical)

CiteScore

6.70

自引率

4.80%

发文量

630

审稿时长

9 weeks

期刊介绍： Open Forum Infectious Diseases provides a global forum for the publication of clinical, translational, and basic research findings in a fully open access, online journal environment. The journal reflects the broad diversity of the field of infectious diseases, and focuses on the intersection of biomedical science and clinical practice, with a particular emphasis on knowledge that holds the potential to improve patient care in populations around the world. Fully peer-reviewed, OFID supports the international community of infectious diseases experts by providing a venue for articles that further the understanding of all aspects of infectious diseases.