Impact of weight variation on the microbiome of yak dams and calves

IF 4 2区生物学 Q2 MICROBIOLOGY

Frontiers in Microbiology Pub Date : 2024-09-18 DOI:10.3389/fmicb.2024.1465992

Hongzhuang Wang, Wangdui Basang, Zhandui Pingcuo, Nan Jiang, Guangming Sun, Shah Nawaz, Yangji Cidan, Yang Liu, Yanbin Zhu, Dunzhu Luosang

{"title":"Impact of weight variation on the microbiome of yak dams and calves","authors":"Hongzhuang Wang, Wangdui Basang, Zhandui Pingcuo, Nan Jiang, Guangming Sun, Shah Nawaz, Yangji Cidan, Yang Liu, Yanbin Zhu, Dunzhu Luosang","doi":"10.3389/fmicb.2024.1465992","DOIUrl":null,"url":null,"abstract":"IntroductionLimited information exists regarding the microbiome composition of yak calves of varying weights. Therefore, this study aimed to investigate the microbiomes of mother-calf pairs with different weight profiles.MethodsFecal and blood samples were collected from both lower-weight (CB) and higher-weight (HB) yak calves, along with their corresponding female yaks (CA, HA).ResultsThe results revealed significantly higher levels of T-AOC (total antioxidant capacity) and GSH-Px (glutathione peroxidase) in HB animals (p &lt; 0.001). Sequencing yielded 652,181 and 643,369 filtered reads in female and calf yaks, respectively. Alpha diversity analysis indicated that Chao1, Faith_pd, and Observed species were significantly higher in CA compared to HA (p &lt; 0.01). Furthermore, nine genera were notably different between HA and CA yaks, including Avispirillum, Fimenecus, CAG-1031, Odoribacter 865974, and Jeotgalicoccus A 310962. Compared to CB yaks, CA animals exhibited significant differences in one phylum and six genera, including CAG-485 (p &lt; 0.05), CAG-83 (p &lt; 0.01), Copromorpha (p &lt; 0.01), Phocaeicola A 858004 (p &lt; 0.05), and UBA2253 (p &lt; 0.05).ConclusionIn summary, higher-weight yak calves demonstrated increased oxidative resistance, and weight profiles were linked to the microbiomes of both female yaks and their calves. These findings offer valuable insights for optimizing yak breeding practices in high-altitude regions.","PeriodicalId":12466,"journal":{"name":"Frontiers in Microbiology","volume":null,"pages":null},"PeriodicalIF":4.0000,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Frontiers in Microbiology","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.3389/fmicb.2024.1465992","RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MICROBIOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

IntroductionLimited information exists regarding the microbiome composition of yak calves of varying weights. Therefore, this study aimed to investigate the microbiomes of mother-calf pairs with different weight profiles.MethodsFecal and blood samples were collected from both lower-weight (CB) and higher-weight (HB) yak calves, along with their corresponding female yaks (CA, HA).ResultsThe results revealed significantly higher levels of T-AOC (total antioxidant capacity) and GSH-Px (glutathione peroxidase) in HB animals (p < 0.001). Sequencing yielded 652,181 and 643,369 filtered reads in female and calf yaks, respectively. Alpha diversity analysis indicated that Chao1, Faith_pd, and Observed species were significantly higher in CA compared to HA (p < 0.01). Furthermore, nine genera were notably different between HA and CA yaks, including Avispirillum, Fimenecus, CAG-1031, Odoribacter 865974, and Jeotgalicoccus A 310962. Compared to CB yaks, CA animals exhibited significant differences in one phylum and six genera, including CAG-485 (p < 0.05), CAG-83 (p < 0.01), Copromorpha (p < 0.01), Phocaeicola A 858004 (p < 0.05), and UBA2253 (p < 0.05).ConclusionIn summary, higher-weight yak calves demonstrated increased oxidative resistance, and weight profiles were linked to the microbiomes of both female yaks and their calves. These findings offer valuable insights for optimizing yak breeding practices in high-altitude regions.

查看原文本刊更多论文

体重变化对牦牛母牛和小牛微生物群的影响

引言有关不同体重的牦牛犊微生物组组成的信息有限。方法收集体重较轻（CB）和体重较重（HB）的牦牛犊及其相应母牦牛（CA、HA）的粪便和血液样本。结果结果显示，HB动物的T-AOC（总抗氧化能力）和GSH-Px（谷胱甘肽过氧化物酶）水平显著较高（p&;lt;0.001）。母牦牛和小牦牛的测序结果分别为 652,181 和 643,369 个过滤读数。α多样性分析表明，与HA相比，CA中的Chao1、Faith_pd和Observed物种明显较多（p&;lt; 0.01）。此外，HA牦牛和CA牦牛有9个属存在明显差异，包括Avispirillum、Fimenecus、CAG-1031、Odoribacter 865974和Jeotgalicoccus A 310962。与 CB 型牦牛相比，CA 型牦牛在 1 个门和 6 个属中表现出显著差异，包括 CAG-485 (p < 0.05)、CAG-83 (p < 0.01)、Copromorpha (p < 0.01)、Phocaeicola A 858004 (p < 0. 05) 和 UBA2253。结论总之，体重较高的牦牛犊表现出更强的抗氧化能力，体重特征与母牦牛及其犊牛的微生物组有关。这些发现为优化高海拔地区的牦牛饲养方法提供了宝贵的见解。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Frontiers in Microbiology MICROBIOLOGY-

CiteScore

7.70

自引率

9.60%

发文量

4837

审稿时长

14 weeks

期刊介绍： Frontiers in Microbiology is a leading journal in its field, publishing rigorously peer-reviewed research across the entire spectrum of microbiology. Field Chief Editor Martin G. Klotz at Washington State University is supported by an outstanding Editorial Board of international researchers. This multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide.