Obstetrical and perinatal outcomes of women with preeclampsia at Woldia Comprehensive Specialized Hospital, Northeast Ethiopia

IF 3.1 3区医学 Q1 MEDICINE, GENERAL & INTERNAL

Frontiers in Medicine Pub Date : 2024-09-18 DOI:10.3389/fmed.2024.1326333

Henok Kumsa, Desalew Mergiyaw

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引用次数: 0

Abstract

BackgroundPreeclampsia is a multisystem disorder that affects pregnant women. Preeclampsia and its complications are the leading causes of maternal and perinatal morbidity and mortality in developing countries. Studies conducted in Ethiopia have primarily concentrated on preeclampsia’s trends and prevalence rather than its obstetrical and perinatal consequences. Thus, this study aimed to determine the risk of adverse obstetric and perinatal outcomes among women with preeclampsia at Woldia Comprehensive Specialized Hospital, Northeast Ethiopia.MethodsA retrospective cohort study was conducted among 140 preeclamptic women and 280 normotensive women who gave birth at Woldia Comprehensive Specialized Hospital between 30 December 2020 and 29 December 2022. Maternal records were retrieved using data-extraction tools. The data were entered into EpiData version 4.6.0.6 and analyzed using SPSS version 26. Binary and multivariable logistic regression models were used to test the associations between independent and outcome variables. The adjusted odds ratio (OR) with a 95% confidence interval (CI) and p-values <0.05 were used to measure the strength of the association and declare the level of statistical significance.ResultsThe odds of at least one adverse obstetric outcome among preeclamptic women were 2.25 times higher than those among normotensive women [AOR: 2.25, 95% CI: (1.06, 4.77)]. In addition, babies born to preeclamptic women were at a higher risk of perinatal death [AOR: 2.90, 95% CI: (1.10, 8.17)], low birth weight [AOR: 3.11, 95% CI: (1.43, 6.7)], birth asphyxia [AOR: 2.53, 95% CI: (1.15, 5.5)], and preterm birth [AOR: 2.21, 95% CI: (1.02, 4.8)] than babies born to normotensive women.ConclusionMore adverse obstetric and perinatal outcomes were observed in women with preeclampsia than those in normotensive women. This study highlights the significantly elevated level of at least one adverse obstetric outcome associated with preeclampsia, low hemoglobin level, and rural residents. Moreover, perinatal death, low birth weight, asphyxia, and preterm birth were significantly associated with preeclampsia.

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埃塞俄比亚东北部 Woldia 综合专科医院子痫前期妇女的产科和围产期结果

背景子痫前期是一种影响孕妇的多系统疾病。子痫前期及其并发症是发展中国家孕产妇和围产期发病率和死亡率的主要原因。在埃塞俄比亚进行的研究主要集中于子痫前期的趋势和发病率，而不是其产科和围产期后果。因此，本研究旨在确定埃塞俄比亚东北部 Woldia 综合专科医院的子痫前期妇女发生不良产科和围产期后果的风险。方法对 2020 年 12 月 30 日至 2022 年 12 月 29 日期间在 Woldia 综合专科医院分娩的 140 名子痫前期妇女和 280 名血压正常妇女进行了回顾性队列研究。使用数据提取工具检索了产妇记录。数据输入 EpiData 4.6.0.6 版，并使用 SPSS 26 版进行分析。二元和多变量逻辑回归模型用于检验自变量与结果变量之间的关联。用调整后的几率比（OR）和 95% 的置信区间（CI）以及 P 值 <0.05 来衡量关联的强度并宣布统计显著性水平。此外，子痫前期妇女所生婴儿围产期死亡[AOR：2.90，95% CI：（1.10，8.17）]、低出生体重[AOR：3.11，95% CI：（1.43，6.7）]、出生窒息[AOR：2.53，95% CI：（1.15，5.5）]和早产的风险更高。结论与血压正常的妇女相比，子痫前期妇女的不良产科和围产期结局更多。这项研究强调，至少一种不良产科结果的发生与子痫前期、低血红蛋白水平和农村居民有关。此外，围产期死亡、低出生体重、窒息和早产与子痫前期也有明显的关联。

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来源期刊

Frontiers in Medicine Medicine-General Medicine

CiteScore

5.10

自引率

5.10%

发文量

3710

审稿时长

12 weeks

期刊介绍： Frontiers in Medicine publishes rigorously peer-reviewed research linking basic research to clinical practice and patient care, as well as translating scientific advances into new therapies and diagnostic tools. Led by an outstanding Editorial Board of international experts, this multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide. In addition to papers that provide a link between basic research and clinical practice, a particular emphasis is given to studies that are directly relevant to patient care. In this spirit, the journal publishes the latest research results and medical knowledge that facilitate the translation of scientific advances into new therapies or diagnostic tools. The full listing of the Specialty Sections represented by Frontiers in Medicine is as listed below. As well as the established medical disciplines, Frontiers in Medicine is launching new sections that together will facilitate - the use of patient-reported outcomes under real world conditions - the exploitation of big data and the use of novel information and communication tools in the assessment of new medicines - the scientific bases for guidelines and decisions from regulatory authorities - access to medicinal products and medical devices worldwide - addressing the grand health challenges around the world