Confocal laser endomicroscopy as a new diagnostic tool for poorly differentiated gastric adenocarcinoma.

IF 1 4区医学 Q3 MEDICINE, GENERAL & INTERNAL

World Journal of Clinical Cases Pub Date : 2024-09-16 DOI:10.12998/wjcc.v12.i26.5845

Giuseppe Evola,Marco Vacante,Francesco R Evola

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引用次数: 0

Abstract

Gastric cancer (GC) is a multifactorial disease, where both environmental and genetic features can have an impact on its occurrence and development. GC represents one of the leading causes of cancer-related deaths worldwide. GC is most frequent in males and is believed to arise from a series of premalignant lesions. The detection of GC at an early stage is crucial because early GC, which is an invasive stomach cancer confined to the mucosal or submucosal lining, may be curable with a reported 5-year survival rate of more than 90%. Advanced GC usually has a poor prognosis despite current treatment standards. The diagnostic efficacy of conventional endoscopy (with light endoscopy) is currently limited. Confocal laser endomicroscopy is a novel imaging technique that allows real-time in vivo histological examination of mucosal surfaces during endoscopy. Confocal laser endomicroscopy may be of great importance in the surveillance of precancerous gastric lesions and in the diagnosis of GC. In this editorial we commented on the article about this topic published by Lou et al in the recent issue of the World Journal of Clinical Cases.

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共焦激光内窥镜作为分化不良胃腺癌的一种新诊断工具。

胃癌（GC）是一种多因素疾病，环境和遗传特征都会对其发生和发展产生影响。胃癌是全球癌症相关死亡的主要原因之一。胃癌多发于男性，据信是由一系列恶性前病变引起的。早期发现胃癌至关重要，因为早期胃癌是一种局限于粘膜或粘膜下层的浸润性胃癌，可以治愈，据报道其 5 年生存率超过 90%。晚期 GC 通常预后较差，尽管目前的治疗标准已经很高。目前，传统内窥镜（包括光内窥镜）的诊断效果有限。共焦激光内窥镜是一种新型成像技术，可在内窥镜检查过程中对粘膜表面进行实时活体组织学检查。共焦激光内窥镜在监测胃癌前病变和诊断胃癌方面可能具有重要意义。在这篇社论中，我们对卢（Lou）等人在最近一期《世界临床病例杂志》（World Journal of Clinical Cases）上发表的有关这一主题的文章进行了评论。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

World Journal of Clinical Cases Medicine-General Medicine

自引率

0.00%

发文量

3384

期刊介绍： The World Journal of Clinical Cases (WJCC) is a high-quality, peer reviewed, open-access journal. The primary task of WJCC is to rapidly publish high-quality original articles, reviews, editorials, and case reports in the field of clinical cases. In order to promote productive academic communication, the peer review process for the WJCC is transparent; to this end, all published manuscripts are accompanied by the anonymized reviewers’ comments as well as the authors’ responses. The primary aims of the WJCC are to improve diagnostic, therapeutic and preventive modalities and the skills of clinicians and to guide clinical practice in clinical cases.