Synthesis of fluorometric carbon nano dots(CNDs) for selective sensing of biologically important Fe3+ and Cu2+ metal ions and evaluating their antioxidant capacity

IF 2.6 4区 化学 Q2 BIOCHEMICAL RESEARCH METHODS
Komal Rajoriya, Pratibha, Abhijeet, Ramhari Meena, Anita Kumari
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Abstract

In this research, CNDs were prepared by a green and cost effective method using Cinnamomum Tamala (bay leaf) as carbon sources. TEM, UV, FTIR, ZETA Potential, PL and Fluorescence methods were used to characterize the produced CNDs and the average particle size is 3.42 nm. This research was conducted on the development of fluorescent sensors for various metal ions, including Fe3+, Cu2+, Zn2+, Ni2+, Pb2+, Cr3+, Mg2+, Na+ 1 and Cd2+. The CNDs demonstrated selective sensing of biologically important Fe+ 3 and Cu+ 2 metal ions. The CNDs antioxidant assay was tasked with DPPH• radical scavenging properties. CNDs made from Cinnamomum Tamala had the highest DPPH free radical scavenging activity at 100 mg/L (42.06%) with the IC50 of 130.68 mg/L. The outcome implies that Indian spices are among the best materials for optical metal ion detection and sensing, and they also have therapeutic benefits.

Abstract Image

用于选择性感测具有生物重要意义的 Fe3+ 和 Cu2+ 金属离子并评估其抗氧化能力的荧光碳纳米点(CNDs)的合成
本研究以月桂叶(Cinnamomum Tamala)为碳源,采用一种绿色且成本效益高的方法制备了 CND。利用 TEM、UV、FTIR、ZETA 电位、PL 和荧光方法对所制备的 CND 进行了表征,其平均粒径为 3.42 nm。这项研究旨在开发针对各种金属离子(包括 Fe3+、Cu2+、Zn2+、Ni2+、Pb2+、Cr3+、Mg2+、Na+ 1 和 Cd2+)的荧光传感器。CNDs 对具有生物重要意义的 Fe+ 3 和 Cu+ 2 金属离子具有选择性感应。CNDs 的抗氧化检测任务是清除 DPPH 自由基。由 Cinnamomum Tamala 制成的 CND 在 100 毫克/升(42.06%)时具有最高的 DPPH 自由基清除活性,IC50 为 130.68 毫克/升。这一结果表明,印度香料是光学金属离子检测和传感的最佳材料之一,而且还具有治疗功效。
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来源期刊
Journal of Fluorescence
Journal of Fluorescence 化学-分析化学
CiteScore
4.60
自引率
7.40%
发文量
203
审稿时长
5.4 months
期刊介绍: Journal of Fluorescence is an international forum for the publication of peer-reviewed original articles that advance the practice of this established spectroscopic technique. Topics covered include advances in theory/and or data analysis, studies of the photophysics of aromatic molecules, solvent, and environmental effects, development of stationary or time-resolved measurements, advances in fluorescence microscopy, imaging, photobleaching/recovery measurements, and/or phosphorescence for studies of cell biology, chemical biology and the advanced uses of fluorescence in flow cytometry/analysis, immunology, high throughput screening/drug discovery, DNA sequencing/arrays, genomics and proteomics. Typical applications might include studies of macromolecular dynamics and conformation, intracellular chemistry, and gene expression. The journal also publishes papers that describe the synthesis and characterization of new fluorophores, particularly those displaying unique sensitivities and/or optical properties. In addition to original articles, the Journal also publishes reviews, rapid communications, short communications, letters to the editor, topical news articles, and technical and design notes.
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