Trace Element Supplementation in Burn Patients: Exploring the Relationship Between Burn Size and Mineral Needs

IF 1.5 4区医学 Q3 CRITICAL CARE MEDICINE

Journal of Burn Care & Research Pub Date : 2024-09-12 DOI:10.1093/jbcr/irae175

Alexander Kurjatko, Colette Galet, Isaac Weigel, Justin Suarez, Lucy Wibbenmeyer

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引用次数: 0

Abstract

Trace element deficiency is an adverse nutritional outcome that can occur with burn injuries, and can interfere with a patient’s recovery. The aim of this study was to review the efficacy of our predominately enteral trace element supplementation strategy and determine the burn size at which patients are at risk for trace element deficiency. We reviewed 53 burn patients admitted to our burn center from August 1, 2019 to May 31, 2022 who had their trace element levels and C-reactive protein monitored in two-week increments. Receiver operating characteristic analysis indicated a 22.1% BSAB cutoff for zinc supplementation to prevent deficiency with 91.7% sensitivity and 92.6% specificity, and a 27.5% BSAB cutoff with 88.9% sensitivity and 81% specificity for copper. No patient in our cohort developed selenium deficiency, regardless of burn size. Patients with greater than 30% body surface area burned developed deficiencies in both zinc and copper within the first two weeks of hospitalization. Our results provide guidance for trace element replacement based on burn size.

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烧伤患者的微量元素补充：探索烧伤面积与矿物质需求之间的关系

微量元素缺乏是烧伤时可能出现的不良营养结果，会影响患者的康复。本研究旨在回顾我们以肠内补充微量元素为主的策略的疗效，并确定患者在何种烧伤面积下有可能出现微量元素缺乏症。我们对烧伤中心从 2019 年 8 月 1 日至 2022 年 5 月 31 日收治的 53 名烧伤患者进行了回顾性研究，这些患者的微量元素水平和 C 反应蛋白以两周为增量进行了监测。接收器操作特征分析表明，补充锌可预防缺乏症的BSAB临界值为22.1%，灵敏度为91.7%，特异度为92.6%；补充铜可预防缺乏症的BSAB临界值为27.5%，灵敏度为88.9%，特异度为81%。在我们的队列中，无论烧伤面积大小，没有患者出现硒缺乏症。烧伤面积大于 30% 的患者在住院后两周内出现锌和铜缺乏症。我们的研究结果为根据烧伤面积补充微量元素提供了指导。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Burn Care & Research 医学-外科

CiteScore

2.60

自引率

21.40%

发文量

535

审稿时长

4-8 weeks

期刊介绍： Journal of Burn Care & Research provides the latest information on advances in burn prevention, research, education, delivery of acute care, and research to all members of the burn care team. As the official publication of the American Burn Association, this is the only U.S. journal devoted exclusively to the treatment and research of patients with burns. Original, peer-reviewed articles present the latest information on surgical procedures, acute care, reconstruction, burn prevention, and research and education. Other topics include physical therapy/occupational therapy, nutrition, current events in the evolving healthcare debate, and reports on the newest computer software for diagnostics and treatment. The Journal serves all burn care specialists, from physicians, nurses, and physical and occupational therapists to psychologists, counselors, and researchers.