Hypoxia-induced BNIP3 facilitates the progression and metastasis of uveal melanoma by driving metabolic reprogramming

IF 14.6 1区生物学 Q1 CELL BIOLOGY

Autophagy Pub Date : 2024-09-12 DOI:10.1080/15548627.2024.2395142

Jie Sun, Jie Ding, Han Yue, Binbin Xu, Akrit Sodhi, Kang Xue, Hui Ren, Jiang Qian

引用次数: 0

Abstract

Uveal melanoma (UM) is an aggressive intraocular malignancy derived from melanocytes in the uvea tract of the eye. Up to 50% of patients with UM develop distant metastases which is usually fatal wi...

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缺氧诱导的 BNIP3 通过驱动代谢重编程促进葡萄膜黑色素瘤的发展和转移

葡萄膜黑色素瘤（UM）是一种侵袭性的眼内恶性肿瘤，来源于眼葡萄膜的黑色素细胞。多达50%的葡萄膜黑色素瘤患者会发生远处转移，而远处转移通常是致命的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Autophagy 生物-细胞生物学

CiteScore

21.30

自引率

2.30%

发文量

277

审稿时长

1 months

期刊介绍： Autophagy is a peer-reviewed journal that publishes research on autophagic processes, including the lysosome/vacuole dependent degradation of intracellular material. It aims to be the premier journal in the field and covers various connections between autophagy and human health and disease, such as cancer, neurodegeneration, aging, diabetes, myopathies, and heart disease. Autophagy is interested in all experimental systems, from yeast to human. Suggestions for specialized topics are welcome. The journal accepts the following types of articles: Original research, Reviews, Technical papers, Brief Reports, Addenda, Letters to the Editor, Commentaries and Views, and Articles on science and art. Autophagy is abstracted/indexed in Adis International Ltd (Reactions Weekly), EBSCOhost (Biological Abstracts), Elsevier BV (EMBASE and Scopus), PubMed, Biological Abstracts, Science Citation Index Expanded, Web of Science, and MEDLINE.