Determination of Cell-Free DNA (cfDNA) Methylation by Methylation-Sensitive High-Resolution Melting (MS-HRM) in Human Plasma for the Diagnosis of Gestational Diabetes Mellitus (GDM)

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-09-02 DOI:10.1080/00032719.2024.2399182

Zhiyu Liu, Yuwei Yang, Yunfei Bai, Qinyu Ge

引用次数: 0

Abstract

Considerable interest has focused on cell-free DNA (cfDNA) methylation for noninvasive prenatal diagnosis. We investigated maternal plasma DNA methylation using a simple protocol. Eighty plasma sam...

查看原文本刊更多论文

用甲基化敏感型高分辨熔融法（MS-HRM）测定人血浆中的无细胞DNA（cfDNA）甲基化情况以诊断妊娠期糖尿病（GDM）

人们对用于无创产前诊断的无细胞 DNA（cfDNA）甲基化非常感兴趣。我们采用简单的方法研究了母体血浆 DNA 甲基化。80份血浆样本...

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.