Comprehensive review of composition, properties, clinical applications, and future perspectives of calcium-enriched mixture (CEM) cement: a systematic analysis
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引用次数: 0
Abstract
This review aims to comprehensively explore calcium-enriched mixture (CEM) cement as a crucial biomaterial in dentistry/endodontics. With its growing clinical relevance, there is a need to evaluate its composition, chemical/physical/biological properties, clinical applications, and future perspectives to provide clinicians/researchers with a detailed understanding of its potential in endodontic procedures. Through systematic analysis of available evidence, we assess the advantages/limitations of CEM cement, offering valuable insights for informed decision-making in dental/endodontic practice. Our findings highlight the commendable chemical/physical properties of CEM cement, including handling characteristics, alkalinity, color stability, bioactivity, biocompatibility, sealing ability, and antimicrobial properties. Importantly, CEM cement has shown the potential in promoting regenerative processes, such as dentinogenesis and cementogenesis. It has demonstrated successful outcomes in various clinical applications, including vital pulp therapy techniques, endodontic surgery, open apices management, root resorption/perforation repair, and as an orifice/root canal obturation material. The efficacy and reliability of CEM cement in diverse clinical scenarios underscore its effectiveness in endodontic practice. However, we emphasize the need for well-designed clinical trials with long-term follow-up to further substantiate the full potential of CEM cement. This review serves as a robust reference for researchers/practitioners, offering an in-depth exploration of CEM cement and its multifaceted roles in contemporary dentistry/endodontics.
本综述旨在全面探讨富钙混合物(CEM)水门汀作为牙科/根管治疗学中的一种重要生物材料的作用。随着其临床相关性的不断提高,有必要对其成分、化学/物理/生物特性、临床应用和未来前景进行评估,以便让临床医生/研究人员详细了解其在牙髓治疗过程中的潜力。通过对现有证据的系统分析,我们评估了 CEM 水泥的优势/局限性,为牙科/牙髓治疗实践中的知情决策提供了宝贵的见解。我们的研究结果强调了 CEM 水泥值得称赞的化学/物理特性,包括操作特性、碱性、颜色稳定性、生物活性、生物相容性、密封能力和抗菌特性。重要的是,CEM 水泥已显示出促进牙本质生成和骨水泥生成等再生过程的潜力。它在各种临床应用中都取得了成功,包括活髓治疗技术、牙髓手术、开放根尖管理、根吸收/穿孔修复,以及作为孔口/根管封堵材料。CEM 骨水泥在各种临床应用中的有效性和可靠性突出表明了它在牙髓治疗实践中的有效性。然而,我们强调有必要进行精心设计的临床试验和长期随访,以进一步证实 CEM 水门汀的全部潜力。这篇综述为研究人员/从业人员提供了有力的参考,深入探讨了 CEM 水泥及其在当代牙科/牙髓病学中的多方面作用。
期刊介绍:
BioMedical Engineering OnLine is an open access, peer-reviewed journal that is dedicated to publishing research in all areas of biomedical engineering.
BioMedical Engineering OnLine is aimed at readers and authors throughout the world, with an interest in using tools of the physical and data sciences and techniques in engineering to understand and solve problems in the biological and medical sciences. Topical areas include, but are not limited to:
Bioinformatics-
Bioinstrumentation-
Biomechanics-
Biomedical Devices & Instrumentation-
Biomedical Signal Processing-
Healthcare Information Systems-
Human Dynamics-
Neural Engineering-
Rehabilitation Engineering-
Biomaterials-
Biomedical Imaging & Image Processing-
BioMEMS and On-Chip Devices-
Bio-Micro/Nano Technologies-
Biomolecular Engineering-
Biosensors-
Cardiovascular Systems Engineering-
Cellular Engineering-
Clinical Engineering-
Computational Biology-
Drug Delivery Technologies-
Modeling Methodologies-
Nanomaterials and Nanotechnology in Biomedicine-
Respiratory Systems Engineering-
Robotics in Medicine-
Systems and Synthetic Biology-
Systems Biology-
Telemedicine/Smartphone Applications in Medicine-
Therapeutic Systems, Devices and Technologies-
Tissue Engineering