Preparation, Structural Analysis, and Growth‐Promoting Effects of Amomum longiligulare Polysaccharide 1‐Mg (II) Complex

IF 4.4 4区医学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY

Macromolecular bioscience Pub Date : 2024-09-13 DOI:10.1002/mabi.202400297

Yijing Chen, Haowen Wu, Chenglong Zhang, Qiyuan Luo, Yun Chen

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引用次数: 0

Abstract

In this study, Amomum longiligulare polysaccharide 1 (ALP1) is used to chelate with magnesium (Mg) to synthesize the ALP1‐Mg (II) complex (ALP1‐Mg). Based on Box‐Behnken response surface design, the optimum technological conditions are 22 mg mL−1 trisodium citrate, 2.10 mol L−1 MgCl2, reaction at 70 °C for 2.9 h, resulting in a maximum Mg content of 2.13%. Next, the physicochemical properties and structural characteristics of ALP1 and ALP1‐Mg are characterized, and the results show that the morphology, conformation, crystallinity, and thermal stability of ALP1‐Mg are changed. In addition, dietary supplementation of 500 mg kg−1 ALP1‐Mg significantly reduces the feed conversion ratio during the grower (15–35 d). Meanwhile, the villus height/crypt depth of the duodenum and ileum are significantly increased, and the relative abundance of Lactobacillus is significantly elevated. Taken together, the results suggest that ALP1‐Mg is a potential growth‐promoting feed additive.

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长日月藻多糖 1-Mg (II) 复合物的制备、结构分析和促进生长作用

本研究利用Amomum longiligulare多糖1（ALP1）与镁（Mg）螯合，合成ALP1-Mg（II）复合物（ALP1-Mg）。根据 Box-Behnken 响应面设计，最佳工艺条件为 22 mg mL-1 柠檬酸三钠、2.10 mol L-1 MgCl2、70 ℃ 反应 2.9 h，镁含量最高为 2.13%。接着，对 ALP1 和 ALP1-Mg 的理化性质和结构特征进行了表征，结果表明 ALP1-Mg 的形态、构象、结晶度和热稳定性都发生了变化。此外，日粮中添加 500 mg kg-1 ALP1-Mg 会显著降低生长期（15-35 d）的饲料转化率。同时，十二指肠和回肠的绒毛高度/绒毛深度明显增加，乳酸杆菌的相对丰度明显提高。综上所述，这些结果表明 ALP1-Mg 是一种潜在的促生长饲料添加剂。

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来源期刊

Macromolecular bioscience 生物-材料科学：生物材料

CiteScore

7.90

自引率

2.20%

发文量

211

审稿时长

1.5 months

期刊介绍： Macromolecular Bioscience is a leading journal at the intersection of polymer and materials sciences with life science and medicine. With an Impact Factor of 2.895 (2018 Journal Impact Factor, Journal Citation Reports (Clarivate Analytics, 2019)), it is currently ranked among the top biomaterials and polymer journals. Macromolecular Bioscience offers an attractive mixture of high-quality Reviews, Feature Articles, Communications, and Full Papers. With average reviewing times below 30 days, publication times of 2.5 months and listing in all major indices, including Medline, Macromolecular Bioscience is the journal of choice for your best contributions at the intersection of polymer and life sciences.