The value of patch testing with plants “as is” in diagnosing plant sensitization

IF 4.8 1区医学 Q2 ALLERGY

Contact Dermatitis Pub Date : 2024-09-19 DOI:10.1111/cod.14680

Evy Paulsen, Charlotte G. Mortz

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引用次数: 0

Abstract

BackgroundThe number of commercially available plant allergens/extracts is limited and therefore patch testing with fresh/dried plant material may be a necessary supplement in diagnosing plant allergy.ObjectivesTo evaluate the usefulness of patch testing with plants “as is” compared to patch testing with commercial and in‐house produced plant test materials and to report on species eliciting positive patch test reactions.Patients/Materials/MethodsConsecutive eczema patients, who were patch tested between January 2019 and December 2023 and who had at least one positive reaction to a plant allergen and/or extract and/or plant “as is” were included in the study.ResultsA total 57 out of 1893 patients tested (3%) were sensitised to plants. Compositae plants were the most frequent sensitizers, followed by tomato, tulipalin A, falcarinol, and Philodendron plants. In 12 patients (21%), the diagnosis was based on patch testing with fresh plants only. Occupational sensitization occurred in 32%. Other sensitizers included Hydrangea, Pelargonium zonale, and Monstera.ConclusionsA large minority of plant‐sensitised patients would have been undiagnosed without patch testing with plants “as is.” Most of the culprit plants were known sensitizers, but not commercially available, and these and new species taken into cultivation makes patch testing with fresh plants unavoidable and worthwhile.

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植物 "原样 "斑贴试验在诊断植物过敏症中的价值

背景市售植物过敏原/提取物的数量有限，因此使用新鲜/干燥植物材料进行斑贴试验可能是诊断植物过敏的必要补充。目的评估使用植物 "原样 "进行斑贴试验与使用市售和自制植物试验材料进行斑贴试验的效用，并报告引起斑贴试验阳性反应的物种。患者/材料/方法在2019年1月至2023年12月期间接受贴敷测试的连续湿疹患者，以及对植物过敏原和/或提取物和/或植物 "原样 "至少有一次阳性反应的患者均被纳入研究范围。结果在1893名接受测试的患者中，共有57人（3%）对植物过敏。最常见的致敏植物是锦葵科植物，其次是番茄、郁金香苷 A、镰刀菌素和蕨类植物。有 12 名患者（21%）的诊断仅基于新鲜植物的斑贴试验。职业性致敏占 32%。结论：如果不对植物进行 "原样 "斑贴试验，少数植物致敏患者可能无法确诊。大多数致敏植物都是已知的致敏物质，但并不是市面上可以买到的，这些植物和新栽培的物种使得使用新鲜植物进行斑贴试验变得不可避免且值得。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Contact Dermatitis 医学-过敏

CiteScore

4.60

自引率

30.90%

发文量

227

审稿时长

4-8 weeks

期刊介绍： Contact Dermatitis is designed primarily as a journal for clinicians who are interested in various aspects of environmental dermatitis. This includes both allergic and irritant (toxic) types of contact dermatitis, occupational (industrial) dermatitis and consumers" dermatitis from such products as cosmetics and toiletries. The journal aims at promoting and maintaining communication among dermatologists, industrial physicians, allergists and clinical immunologists, as well as chemists and research workers involved in industry and the production of consumer goods. Papers are invited on clinical observations, diagnosis and methods of investigation of patients, therapeutic measures, organisation and legislation relating to the control of occupational and consumers".