Effects of long-term lithium therapy on kidney functioning in mood disorders: A population-based historical cohort study

IF 5 2区医学 Q1 CLINICAL NEUROLOGY

Bipolar Disorders Pub Date : 2024-09-16 DOI:10.1111/bdi.13501

Ajay K. Parsaik, Aanchal Chaudhary, Shivy Sharma, Brooke Ellen Delgoffe, Rachel Gabor, Balwinder Singh

引用次数: 0

Abstract

Lithium is Food and Drug Administration-approved for bipolar disorder (BD) and is also used in depressive disorders but is underutilized due to concerns about chronic kidney disease (CKD). We explored clinical and demographic profiles of patients on long-term lithium therapy (LTLT) and assessed kidney function. Our aims were to identify the predictors for CKD stage ≥3 and the impact of lithium discontinuation post-CKD diagnosis.

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长期锂疗法对情绪障碍患者肾功能的影响：基于人群的历史队列研究

锂是美国食品和药物管理局批准用于治疗双相情感障碍（BD）的药物，也可用于治疗抑郁症，但由于人们对慢性肾脏疾病（CKD）的担忧，锂的使用率并不高。我们研究了长期锂疗法（LTLT）患者的临床和人口统计学特征，并评估了肾功能。我们的目的是确定 CKD 分期≥3 的预测因素以及 CKD 诊断后停用锂的影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Bipolar Disorders 医学-精神病学

CiteScore

8.20

自引率

7.40%

发文量

审稿时长

6-12 weeks

期刊介绍： Bipolar Disorders is an international journal that publishes all research of relevance for the basic mechanisms, clinical aspects, or treatment of bipolar disorders and related illnesses. It intends to provide a single international outlet for new research in this area and covers research in the following areas: biochemistry physiology neuropsychopharmacology neuroanatomy neuropathology genetics brain imaging epidemiology phenomenology clinical aspects and therapeutics of bipolar disorders Bipolar Disorders also contains papers that form the development of new therapeutic strategies for these disorders as well as papers on the topics of schizoaffective disorders, and depressive disorders as these can be cyclic disorders with areas of overlap with bipolar disorders. The journal will consider for publication submissions within the domain of: Perspectives, Research Articles, Correspondence, Clinical Corner, and Reflections. Within these there are a number of types of articles: invited editorials, debates, review articles, original articles, commentaries, letters to the editors, clinical conundrums, clinical curiosities, clinical care, and musings.